Sustained virologic response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more

BL Pearlman, N Traub - Clinical infectious diseases, 2011 - academic.oup.com
Sustained virologic response (SVR) is defined as aviremia 24 weeks after completion of
antiviral therapy for chronic hepatitis C virus (HCV) infection. In analyses of SVR durability …

What is killing people with hepatitis C virus infection?

J Grebely, GJ Dore - Seminars in liver disease, 2011 - thieme-connect.com
The burden of hepatitis C virus (HCV)-related morbidity and mortality continues to rise.
Progression to advanced liver disease among HCV-infected individuals generally requires …

A sustained virologic response reduces risk of all-cause mortality in patients with hepatitis C

LI Backus, DB Boothroyd, BR Phillips, P Belperio… - Clinical …, 2011 - Elsevier
Background & Aims The effectiveness of hepatitis C virus (HCV) treatment with pegylated
interferon and ribavirin usually is evaluated by the surrogate end point of sustained virologic …

[HTML][HTML] The current economic burden of cirrhosis

GW Neff, CW Duncan, ER Schiff - Gastroenterology & hepatology, 2011 - ncbi.nlm.nih.gov
Cirrhosis is a worldwide problem that is associated with a substantial economic burden.
Hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, and alcoholic liver …

Effects of a sustained virologic response on outcomes of patients with chronic hepatitis C

V Ng, S Saab - Clinical Gastroenterology and Hepatology, 2011 - Elsevier
For patients with chronic hepatitis C virus infection, the goal of antiviral therapy is to achieve
a sustained virologic response (SVR). We review the durability of the SVR and its effects on …

Excess liver‐related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

HA Innes, SJ Hutchinson, S Allen… - …, 2011 - Wiley Online Library
Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature:(1) Few
data exist comparing post‐treatment liver‐related mortality/morbidity in HCV‐sustained …

Incident hepatitis C virus infection among US HIV-infected men enrolled in clinical trials

LE Taylor, M Holubar, K Wu, RJ Bosch… - Clinical infectious …, 2011 - academic.oup.com
Background. Outbreaks of sexually transmitted hepatitis C virus (HCV) infection have been
reported among human immunodeficiency virus (HIV)–infected men who have sex with men …

Effects of interferon treatment on development and progression of hepatocellular carcinoma in patients with chronic virus infection: A meta‐analysis of randomized …

CH Zhang, GL Xu, WD Jia, JS Li… - International journal of …, 2011 - Wiley Online Library
Available literature on the effects of interferon (IFN) treatment on development and
progression of hepatocellular carcinoma (HCC) in patients with chronic virus infection …

Acute hepatitis C virus in an HIV clinic: a screening strategy, risk factors, and perception of risk

LE Taylor, AK DeLong, MA Maynard… - AIDS patient care and …, 2011 - liebertpub.com
Acute hepatitis C virus (HCV) infection is being acquired undetected among HIV-infected
individuals. A practical way to regularly screen HIV-infected patients for acute HCV …

Peginterferon alfa-2a is superior to peginterferon alfa-2b in the treatment of naive patients with hepatitis C virus infection: meta-analysis of randomized controlled trials

AK Singal, SC Jampana, BS Anand - Digestive diseases and sciences, 2011 - Springer
Background Pegylated interferon (PEGIFN) and ribavirin combination is the standard of care
for the treatment of chronic hepatitis C virus (HCV) infection. Studies comparing the efficacy …