Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation
AC Raddant, AF Russo - Expert reviews in molecular medicine, 2011 - cambridge.org
Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …
Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitrostudy
YT Lin, LS Ro, HL Wang, JC Chen - Journal of neuroinflammation, 2011 - Springer
Background During inflammation, immune cells accumulate in damaged areas and release
pro-inflammatory cytokines and neurotrophins. Brain-derived neurotrophic factor (BDNF) …
pro-inflammatory cytokines and neurotrophins. Brain-derived neurotrophic factor (BDNF) …
IL-1β Stimulates COX-2 Dependent PGE2 Synthesis and CGRP Release in Rat Trigeminal Ganglia Cells
L Neeb, P Hellen, C Boehnke, J Hoffmann… - PloS one, 2011 - journals.plos.org
Objective Pro-inflammatory cytokines like Interleukin-1 beta (IL-1β) have been implicated in
the pathophysiology of migraine and inflammatory pain. The trigeminal ganglion and …
the pathophysiology of migraine and inflammatory pain. The trigeminal ganglion and …
Tumor necrosis factor-α induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions
XC Zhang, V Kainz, R Burstein, D Levy - PAIN®, 2011 - Elsevier
The proinflammatory cytokine TNF-α has been shown to promote activation and
sensitization of primary afferent nociceptors. The downstream signaling processes that play …
sensitization of primary afferent nociceptors. The downstream signaling processes that play …
Tumor necrosis factor-α increases brain-derived neurotrophic factor expression in trigeminal ganglion neurons in an activity-dependent manner
E Bałkowiec-Iskra, A Vermehren-Schmaedick… - Neuroscience, 2011 - Elsevier
Many chronic trigeminal pain conditions, such as migraine or temporo-mandibular disorders,
are associated with inflammation within peripheral endings of trigeminal ganglion (TG) …
are associated with inflammation within peripheral endings of trigeminal ganglion (TG) …
Organ culture of the trigeminal ganglion induces enhanced expression of calcitonin gene-related peptide via activation of extracellular signal-regulated protein kinase …
J Tajti, A Kuris, L Vécsei, CB Xu, L Edvinsson - Cephalalgia, 2011 - journals.sagepub.com
Background and objective: Clinical and experimental studies have revealed a central role of
calcitonin gene-related peptide (CGRP) in primary headaches. The role of extracellular …
calcitonin gene-related peptide (CGRP) in primary headaches. The role of extracellular …
Treatment of mast cells with carbon dioxide suppresses degranulation via a novel mechanism involving repression of increased intracellular calcium levels
JW Strider, CG Masterson, PL Durham - Allergy, 2011 - Wiley Online Library
To cite this article: Strider JW, Masterson CG, Durham PL. Treatment of mast cells with
carbon dioxide suppresses degranulation via a novel mechanism involving repression of …
carbon dioxide suppresses degranulation via a novel mechanism involving repression of …
[HTML][HTML] Tumor necrosis factor-α increases BDNF expression in trigeminal ganglion neurons in an activity-dependent manner
E Bałkowiec-Iskra, A Vermehren-Schmaedick… - …, 2011 - ncbi.nlm.nih.gov
Many chronic trigeminal pain conditions, such as migraine or temporo-mandibular disorders,
are associated with inflammation within peripheral endings of trigeminal ganglion (TG) …
are associated with inflammation within peripheral endings of trigeminal ganglion (TG) …
Tumor necrosis factor alpha and non-inflammatory sensitization of masseter muscle nociceptors
AW Hakim - 2011 - open.library.ubc.ca
Behavioral evidence in rats indicates that injection of tumor necrosis factor alpha (TNFalpha
into skeletal muscle results in a prolonged mechanical sensitization without gross …
into skeletal muscle results in a prolonged mechanical sensitization without gross …