Myelodysplastic syndromes and related disorders (myelodysplasia) are a heterogeneous
group of myeloid neoplasms showing deregulated blood cell production with evidence of …

Little is known of the genetic architecture of cancer at the subclonal and single-cell level or
in the cells responsible for cancer clone maintenance and propagation. Here we have …

Neuroblastoma is one of the most common solid cancers among children. Prognosis of
advanced neuroblastoma is still poor despite the recent advances in chemo/radiotherapies …

We report identification of a novel genetic locus (GLC1P) for normal tension glaucoma
(NTG) on chromosome 12q14 using linkage studies of an African-American pedigree …

Idiopathic aplastic anemia (AA) is a common cause of acquired BM failure. Although
autoimmunity to hematopoietic progenitors is thought to be responsible for its pathogenesis …

Background MicroRNAs (miRNAs) are non-coding gene transcripts involved in post-
transcriptional regulation of genes. Recent studies identified miRNAs as important …

In aplastic anemia (AA), contraction of the stem cell pool may result in oligoclonality, while in
myelodysplastic syndromes (MDS) a single hematopoietic clone often characterized by …

The statistical analysis of array comparative genomic hybridization (CGH) data has now
shifted to the joint assessment of copy number variations at the cohort level. Considering …

Objective. Multiple genetic syndromes are caused by recurrent chromosomal microdeletions
or microduplications. The increasing use of high‐resolution microarrays in clinical analysis …

Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly Page 1
Clin Genet 2011: 79: 296–299 Printed in Singapore. All rights reserved © 2011 John Wiley & …