Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner
MD Gahete, J Cordoba-Chacon, CV Anadumaka… - …, 2011 - academic.oup.com
A unique mouse model was developed with elevated endogenous GH (2-to 3-fold) and IGF-I
(1.2-to 1.4-fold), due to somatotrope-specific Cre-mediated inactivation of IGF-I receptor …
(1.2-to 1.4-fold), due to somatotrope-specific Cre-mediated inactivation of IGF-I receptor …
生长激素对机体营养代谢和免疫功能影响的研究进展
姜鹏君， 郭光华 - 中华烧伤杂志, 2011 - cqvip.com
生长激素(GH) 是体内重要的合成类激素, 对生长发育及代谢起着重要作用. 近年来, GH
越来越多地应用于严重烧(创) 伤, 肝硬化低蛋白血症, 肾病综合征(NS) 等多个方面 …
越来越多地应用于严重烧(创) 伤, 肝硬化低蛋白血症, 肾病综合征(NS) 等多个方面 …
Effects of Growth Hormone (GH) Overexpression in Signaling Cascades Involved in Promotion of Cell Proliferation and Survival
L González, JG Miquet, AI Sotelo - Contemp. Asp. Endocrinol, 2011 - books.google.com
This chapter will describe the effects of long term exposure to growth hormone (GH) at the
molecular level in the liver. Expression and activation of intermediates involved in GH …
molecular level in the liver. Expression and activation of intermediates involved in GH …
Estudo dos efeitos endócrinos e parácrinos do hormônio de crescimento após administração de DNA plasmidial em modelos animais de terapia gênica
E Higuti - 2011 - teses.usp.br
Nosso grupo tem estudado uma estratégia alternativa de tratamento para a deficiência de
hormônio de crescimento (DGH), utilizando a administração in vivo do plasmídeo pUC-UBI …
hormônio de crescimento (DGH), utilizando a administração in vivo do plasmídeo pUC-UBI …