The mesenchymal elements of the intestinal lamina propria reviewed here are the
myofibroblasts, fibroblasts, mural cells (pericytes) of the vasculature, bone marrow–derived …

Hepatic stellate cells (HSCs) were recently postulated as a component of the prometastatic
liver microenvironment, because they can transdifferentiate into highly proliferative and …

Regulatory T cells (Tregs) contribute significantly to the tolerogenic nature of the liver. The
mechanisms, however, underlying liver-associated Treg induction are still elusive. We …

Although organ transplants have been applied for decades, outcomes of somatic cell
transplants remain disappointing, presumably due to lack of appropriate supporting stromal …

Activated hepatic stellate cells (HSCs) play a central role in the hepatic fibrosis and cirrhosis.
Recently, HSCs were reported to have strong immune modulatory activities. However, the …

The liver has a role in T cell tolerance induction, which is mainly achieved through the
functions of tolerogenic hepatic antigen‐presenting cells (APCs) and regulatory T cells …

Hepatic stellate cells (HSCs) are important part of the local 'stem cell niche'for hepatic
progenitor cells (HPCs) and hepatocytes. However, it is unclear as to whether the products …

The stroma of hepatocellular carcinoma (HCC) is markedly infiltrated with activated hepatic
stellate cells (HSCs), and associated invasion and metastasis of HCC. However, little is …

In the steady state, hepatic antigen (Ag)-presenting cells (APC) generally dampen systemic
inflammatory responses to gut-derived Ags. Our studies focus on the role of specific liver …

Hepatic stellate cells (HSCs; also known as fat-storing cells, lipocytes, Ito cells,
perisinusoidal cells) are located in the perisinusoidal space under the fenestrated …