Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis

FX Blanc, T Sok, D Laureillard, L Borand… - … England Journal of …, 2011 - Mass Medical Soc
Background Tuberculosis remains an important cause of death among patients infected with
the human immunodeficiency virus (HIV). Robust data are lacking with regard to the timing …

[HTML][HTML] High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African …

D Nakanjako, I Ssewanyana, H Mayanja-Kizza… - BMC infectious …, 2011 - Springer
Background Antiretroviral therapy (ART) partially corrects immune dysfunction associated
with HIV infection. The levels of T-cell immune activation and exhaustion after long-term …

Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa

MD Nglazi, SD Lawn, R Kaplan, K Kranzer… - JAIDS Journal of …, 2011 - journals.lww.com
Objectives: To assess sustainability of programmatic outcomes in a community-based
antiretroviral therapy (ART) service in South Africa during 7 years of scale-up. Methods …

A missing piece in the puzzle: HIV in mature adults in sub-Saharan Africa

PC Mutevedzi, ML Newell - Future virology, 2011 - Taylor & Francis
Healthcare and social needs for mature adults aged 50 years or older differ from those of
younger adults due to stigma concerning HIV in older people, beliefs that engagement in …

[HTML][HTML] Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults

PC Mutevedzi, RJ Lessells, AJ Rodger, ML Newell - PloS one, 2011 - journals.plos.org
Objective To assess whether treatment outcomes vary with age for adults receiving
antiretroviral therapy (ART) in a large rural HIV treatment cohort. Design Retrospective …

Antiretroviral therapy refusal among newly diagnosed HIV-infected adults

IT Katz, T Essien, ET Marinda, GE Gray, DR Bangsberg… - Aids, 2011 - journals.lww.com
Objective: To determine rates and predictors of treatment refusal in newly identified HIV-
infected individuals in Soweto, South Africa. Design: It is designed as a cross-sectional …

[HTML][HTML] Late entry into HIV care: estimated impact on AIDS mortality rates in Brazil, 2003–2006

A Grangeiro, MM Escuder, PR Menezes, R Alencar… - PLoS …, 2011 - journals.plos.org
Background Worldwide, a high proportion of HIV-infected individuals enter into HIV care
late. Here, our objective was to estimate the impact that late entry into HIV care has had on …

Potential utility of empirical tuberculosis treatment for HIV-infected patients with advanced immunodeficiency in high TB-HIV burden settings [Unresolved issues]

SD Lawn, H Ayles, S Egwaga… - … of tuberculosis and …, 2011 - ingentaconnect.com
The human immunodeficiency virus (HIV) and HIV-associated tuberculosis (TB-HIV)
epidemics remain uncontrolled in many resource-limited regions, especially in sub-Saharan …

[HTML][HTML] Long-term CD4+ lymphocyte response following HAART initiation in a US Military prospective cohort

AR Lifson, EM Krantz, LE Eberly, MJ Dolan… - AIDS research and …, 2011 - Springer
Background Among HIV-infected persons initiating highly active antiretroviral therapy
(HAART), early CD4+ lymphocyte count increases are well described. However, whether …

Changing predictors of mortality over time from cART start: implications for care

CJ Hoffmann, KL Fielding, V Johnston… - JAIDS Journal of …, 2011 - journals.lww.com
Changing Predictors of Mortality Over Time From cART Start:... : JAIDS Journal of Acquired
Immune Deficiency Syndromes Changing Predictors of Mortality Over Time From cART Start …