Modifications in the polymerase genes of a swine-like triple-reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 viruses
L Pena, AL Vincent, J Ye, JR Ciacci-Zanella… - Journal of …, 2011 - Am Soc Microbiol
ABSTRACT On 11 June 2009, the World Health Organization (WHO) declared that the
outbreaks caused by novel swine-origin influenza A (H1N1) virus had reached pandemic …
outbreaks caused by novel swine-origin influenza A (H1N1) virus had reached pandemic …
[HTML][HTML] New strategies for the development of H5N1 subtype influenza vaccines: progress and challenges
J Steel - BioDrugs, 2011 - Springer
The emergence and spread of highly pathogenic avian influenza (H5N1) viruses among
poultry in Asia, the Middle East, and Africa have fueled concerns of a possible human …
poultry in Asia, the Middle East, and Africa have fueled concerns of a possible human …
Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner
MP Walkiewicz, D Basu, JJ Jablonski… - Journal of general …, 2011 - microbiologyresearch.org
Influenza virus non-structural protein 1 (NS1) is the centrepiece of the viral response to the
host interferon (IFN) system. NS1 has been demonstrated previously to be a potential …
host interferon (IFN) system. NS1 has been demonstrated previously to be a potential …
Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs
Humoral and cellular immune responses to inactivated swine influenza virus (SIV) vaccine
were evaluated and compared. Fifty 3-week-old weaned pigs were randomly divided into …
were evaluated and compared. Fifty 3-week-old weaned pigs were randomly divided into …
MDCK cell line with inducible allele B NS1 expression propagates delNS1 influenza virus to high titres
R Van Wielink, MM Harmsen, DE Martens… - Vaccine, 2011 - Elsevier
Influenza A viruses lacking the gene encoding the non-structural NS1 protein (delNS1) have
potential use as live attenuated vaccines. However, due to the lack of NS1, virus replication …
potential use as live attenuated vaccines. However, due to the lack of NS1, virus replication …
Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1)
N Takeyama, K Minari, M Kajihara, N Isoda… - Veterinary …, 2011 - Elsevier
H5 and H7 highly pathogenic avian influenza virus (HPAIV) represent a major global
concern in poultries and human health. Avian influenza (AI) vaccines are available but not …
concern in poultries and human health. Avian influenza (AI) vaccines are available but not …
Genetic characterization of swine influenza viruses (H3N2) isolated from Minnesota in 2006–2007
SRP Kumar, L Deflube, M Biswas, R Shobana… - Virus genes, 2011 - Springer
Abstract Triple-reassortant (TR) H3N2 swine influenza viruses (SIV) are a major cause of
respiratory disease in swine worldwide, causing considerable morbidity and mortality …
respiratory disease in swine worldwide, causing considerable morbidity and mortality …
Control and characterization of influenza A viruses in swine
SE Detmer - 2011 - conservancy.umn.edu
Between 1958 and 2005, there were 37 human cases of zoonotic swine-origin influenza A
virus (IAV) infection reported (Myers et al 2007; Van Reeth 2007). A majority of these …
virus (IAV) infection reported (Myers et al 2007; Van Reeth 2007). A majority of these …
Получение и характеристика реассортантного вируса гриппа А с гемагглютинином Н5 и остальными генами от апатогенного вируса H6N2
ЕЮ Боравлева, НФ Ломакина, ЕА Кропоткина… - Вопросы …, 2011 - elibrary.ru
Двухступенчатым способом получен экспериментальный реассортантный вакцинный
штамм вируса гриппа VN-gull (H5N2), содержащий гемагглютинин Н5 с удаленным …
штамм вируса гриппа VN-gull (H5N2), содержащий гемагглютинин Н5 с удаленным …