Multiple Sclerosis (MS) is the most common demyelinating disease of the central nervous
system. Although the etiology and the pathogenesis of MS has been extensively …

Multiple sclerosis (MS) is a chronic neurologic disease with onset occurring predominantly
in young adults. As such, the disease evolves throughout several decades and the affected …

Background: There is increasing evidence on cerebrospinal fluid (CSF) oligoclonal IgM
(OCIgM) predicting a more aggressive disease course in relapsing–remitting Multiple …

Purpose To illustrate how structural equation modeling (SEM) can be used for response shift
detection with random measurement occasions and health state operationalized as fixed …

Although a small number of patients have slowly progressive neurologic deficits from the
onset of the disease (primary progressive multiple sclerosis [PPMS]), most (85%) experience …

Background: Early life events have been suggested to influence multiple sclerosis (MS)
susceptibility, and to potentially modulate its clinical course. We assessed vitamin D-related …

Objective: To illustrate different perspectives on response shift with cancer patients' health-
related quality-of-life (HRQoL) data. In measurement perspective, the focus is on bias in the …

Multiple Sclerosis (MS) is a demyelinating, degenerative disease of themcentral nervous
system. It is the leading cause of disability in young adults for which there is no cure. In a …

Primárne progresívna roztrúsená skleróza (PPMS) predstavuje približne 10–15% pacientov
so sclerosis multiplex. Patofyziológia ochorenia nie je doteraz prebádaná, predpokladá sa …

Aunque el cuadro clínico de la esclerosis múltiple (EM) se describe clásicamente como un
trastorno remitente recurrente de inicio en adultos jóvenes y que afecta a múltiples regiones …