Over the past 20 years, stem cell technologies have become an increasingly attractive
option to investigate and treat neurodegenerative diseases. In the current review, we …

Introduction: Macrophage activation is a hallmark of spinal cord injury (SCI) pathology. CNS
macrophages, derived from resident microglia and blood monocytes, are ubiquitous …

Object Many experimental studies on spinal cord injuries (SCIs) support behavioral
improvement after Schwann cell treatment. This study was conducted to evaluate safety …

Geron recently announced that it had begun enrolling patients in the world's first-in-human
clinical trial involving cells derived from human embryonic stem cells (hESCs). This trial …

Spinal cord injury (SCI) occurs in the most productive part of life. Treatment options for
treatment of chronic SCI are few and have limited impact on clinical outcome. Central …

Olfactory ensheathing cells (OEC) have been shown to stimulate regeneration, myelination
and functional recovery in different spinal cord injury models. However, recent reports from …

Background Spinal cord injury is a serious and debilitating condition, affecting millions of
people worldwide. Long seen as a permanent injury, recent advances in stem cell research …

This review describes the changes of spinal neuronal function that occur after a motor
complete spinal cord injury (cSCI) in humans. In healthy subjects, polysynaptic spinal reflex …

In recent years, olfactory ensheathing cells (OECs) have been used as a therapeutic
strategy to repair the anatomical structure and promote the function recovery of injured …

Introduction A large number of different cells including embryonic and adult stem cells have
been transplanted into animal models of spinal cord injury, and in many cases these …