Bone marrow‐derived mesenchymal stem cells (MSCs) are multipotent progenitors that can
commit to osteoblast, chondrocyte, adipocyte, and several other lineages. The proper …

Osteoblasts are mononucleated cells that are derived from mesenchymal stem cells and that
are responsible for the synthesis and mineralization of bone during initial bone formation …

Despite advances in the knowledge of tooth morphogenesis and differentiation, relatively
little is known about the aetiology and molecular mechanisms underlying supernumerary …

Background An effective immune system, especially during the inflammatory phase,
putatively influences the quality and likelihood of bone healing. If and how this is reflected …

As the average age of the population grows, the incidence of osteoporosis and skeletal
diseases continues to rise. Current treatment options for skeletal repair include …

Since the discovery of SOX9 mutations in the severe human skeletal malformation syndrome
campomelic dysplasia in 1994, Sox9 was shown to be both required and sufficient for …

Osteosarcoma is an aggressive but ill‐understood cancer of bone that predominantly affects
adolescents. Its rarity and biological heterogeneity have limited studies of its molecular …

Introduction In contrast to its role in breast cancer (BCa) initiation, estrogen signaling has a
protective effect in later stages, where estrogen receptor (ER) α loss associates with …

Osteoporosis is a multifactorial skeletal disorder characterized by decreased bone mass and
deteriorated microarchitecture that lead to increased risk of fracture. The disuse …

The primary focus of this article is to review intramembranous bone development, that is,
ossification that takes place directly. Comparisons with endochondral ossification …