Chimeric aptamers in cancer cell-targeted drug delivery
Aptamers are single-stranded structured oligonucleotides (DNA or RNA) that can bind to a
wide range of targets (“apatopes”) with high affinity and specificity. These nucleic acid …
wide range of targets (“apatopes”) with high affinity and specificity. These nucleic acid …
Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To
JA Johnson, YY Lu, AO Burts, YH Lim… - Journal of the …, 2011 - ACS Publications
The combination of highly efficient polymerizations with modular “click” coupling reactions
has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we …
has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we …
Novel nanotechnology approaches to diagnosis and therapy of ovarian cancer
PS Kim, S Djazayeri, R Zeineldin - Gynecologic Oncology, 2011 - Elsevier
OBJECTIVE: Ovarian carcinoma is the leading cause of death from gynecologic
malignancies, which is a direct outcome of missing its diagnosis at an early stage …
malignancies, which is a direct outcome of missing its diagnosis at an early stage …
Building nanostructures using RAFT polymerization
Reversible addition fragmentation chain transfer (RAFT) polymerization is one of the most
extensively studied controlled/living radical polymerization methods that has been used to …
extensively studied controlled/living radical polymerization methods that has been used to …
Rapidly disassembling nanomicelles with disulfide-linked PEG shells for glutathione-mediated intracellular drug delivery
HY Wen, HQ Dong, W Xie, YY Li, K Wang… - Chemical …, 2011 - pubs.rsc.org
The synthesis and biological efficacy of novel nanomicelles that rapidly disassemble and
release their encapsulated payload intracellularly under tumor-relevant glutathione (GSH) …
release their encapsulated payload intracellularly under tumor-relevant glutathione (GSH) …
Conjugation of two complementary anti-cancer drugs confers molecular hydrogels as a co-delivery system
Conjugation of two complementary anti-cancer drugs confers molecular hydrogels as a co-delivery
system - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC16250K Royal …
system - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC16250K Royal …
Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive release mechanism
XQ Li, HY Wen, HQ Dong, WM Xue… - Chemical …, 2011 - pubs.rsc.org
Self-assembling nanomicelles of a novel camptothecin prodrug engineered with a redox-responsive
release mechanism - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC12495A …
release mechanism - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC12495A …
Platinum (IV)-coordinate polymers as intracellular reduction-responsive backbone-type conjugates for cancer drug delivery
J Yang, W Liu, M Sui, J Tang, Y Shen - Biomaterials, 2011 - Elsevier
Platinum (IV)-coordinate polymers were synthesized by condensation polymerization using
diamminedichlorodihydroxyplatinum (DHP) or its dicarboxyl derivative …
diamminedichlorodihydroxyplatinum (DHP) or its dicarboxyl derivative …
Construction of surfactant-like tetra-tail amphiphilic peptide with RGD ligand for encapsulation of porphyrin for photodynamic therapy
JX Chen, HY Wang, C Li, K Han, XZ Zhang, RX Zhuo - Biomaterials, 2011 - Elsevier
A surfactant-like tetra-tail amphiphilic peptide,[(C18) 2K] 2KR8GRGDS was designed and
synthesized for targeted drug delivery. The resulting peptide–amphiphile, consisting of four …
synthesized for targeted drug delivery. The resulting peptide–amphiphile, consisting of four …
Self‐assembly strategy for the preparation of polymer‐based nanoparticles for drug and gene delivery
S Chen, SX Cheng, RX Zhuo - Macromolecular bioscience, 2011 - Wiley Online Library
Nanoparticulate drug‐delivery systems have attained much importance because of their
injectable property, the possibility to achieve passive targeting and active targeting, and …
injectable property, the possibility to achieve passive targeting and active targeting, and …