Immune responses to rotavirus infection and vaccination and associated correlates of protection

U Desselberger, HI Huppertz - Journal of Infectious Diseases, 2011 - academic.oup.com
Group A rotavirus (RV) strains are a major cause of acute gastroenteritis (AGE) in infants
and young children worldwide [1]. RV disease accounts for more than one-third of all …

Whole-genomic analysis of rotavirus strains: current status and future prospects

S Ghosh, N Kobayashi - Future microbiology, 2011 - Taylor & Francis
Studies on genetic diversity of rotaviruses have been primarily based on the genes
encoding the antigenically significant VP7 and VP4 proteins. Since the rotavirus genome …

[HTML][HTML] Gastroenteritis in childhood: a retrospective study of 650 hospitalized pediatric patients

V Wiegering, J Kaiser, D Tappe, B Weißbrich… - International Journal of …, 2011 - Elsevier
Background Acute diarrhea continues to be an important cause of hospitalization in young
children, and deaths still occur as a result. We reviewed a large cohort of hospitalized …

The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3

A Sen, AJ Pruijssers, TS Dermody… - Journal of …, 2011 - Am Soc Microbiol
In mouse embryonic fibroblasts (MEFs), the bovine rotavirus (UK strain) but not the simian
rhesus rotavirus (RRV) robustly triggers beta interferon (IFN-β) secretion, resulting in an IFN …

Novel probiotic Bifidobacterium longum subsp. infantis CECT 7210 strain active against rotavirus infections

JA Moreno Muñoz, E Chenoll, B Casinos… - Applied and …, 2011 - Am Soc Microbiol
Rotavirus is the leading cause of severe acute gastroenteritis among children worldwide. It
is well known that breast-feeding and vaccination afford infants protection. Since breast …

Mechanisms of action of zinc in acute diarrhea

RB Canani, V Buccigrossi… - Current opinion in …, 2011 - journals.lww.com
Mechanisms of action of zinc in acute diarrhea : Current Opinion in Gastroenterology
Mechanisms of action of zinc in acute diarrhea : Current Opinion in Gastroenterology Log in or …

Rotavirus vaccines: update on global impact and future priorities

C Yen, JE Tate, MM Patel, MM Cortese… - Human …, 2011 - Taylor & Francis
Early rotavirus vaccine adopter countries in the Americas, Europe, and in Australia have
documented substantial declines in rotavirus disease burden following the introduction of …

The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells

E Delorme-Axford, CB Coyne - Viruses, 2011 - mdpi.com
Many diverse viruses target a polarized epithelial monolayer during host invasion. The
polarized epithelium is adept at restricting the movement of solutes, ions, macromolecules …

Immunobiotic lactic acid bacteria beneficially regulate immune response triggered by poly (I: C) in porcine intestinal epithelial cells

S Hosoya, J Villena, T Shimazu, M Tohno, H Fujie… - Veterinary …, 2011 - Springer
This study analyzed the functional expression of TLR3 in various gastrointestinal tissues
from adult swine and shows that TLR3 is expressed preferentially in intestinal epithelial cells …

Full genomic analysis of a G8P [1] rotavirus strain isolated from an asymptomatic infant in Kenya provides evidence for an artiodactyl‐to‐human interspecies …

S Ghosh, Z Gatheru, J Nyangao… - Journal of medical …, 2011 - Wiley Online Library
Abstract Group A rotavirus (GAR) G8P [1] strains, found sometimes in cattle, have been
reported rarely from humans. Therefore, analysis of the full genomes of human G8P [1] …