Human embryonic stem cells (hESCs) hold enormous promise for regenerative medicine.
Typically, hESC-based applications would require their in vitro differentiation into a …

The transmembrane protein CD133 and its extracellular epitope AC133 are controversial
cancer markers. In glioma, AC133 demarcates a subpopulation of stem‐like tumor cells, so …

Introduction Despite the various therapeutic combinations and the emergence of new
targeted therapies, there is still no curative treatment for all stages of colorectal cancer …

Background Cancer stem-like cells (CSCs) in colorectal cancers (CRC) may account for the
failure of treatments because they are resistant to many current anticancer therapies …

Retinal degenerative diseases are a major cause of untreatable blindness. Stem cell
therapy to replace lost photoreceptors represents a feasible future treatment. We previously …

Abstract CD133 (prominin-1) is a transmembrane glycoprotein expressed on the surface of
normal and cancer stem cells (tumor-initiating cells), progenitor cells, rod photoreceptor cells …

We isolated and expanded stem cells from dental pulp from extracted third molars using an
innovative culture method consisting of low serum-containing medium supplemented with …

The differentiation of stem cells is a fundamental process in cell biology and understanding
its mechanism might open a new avenue for therapeutic strategies. Using an ex vivo co …

The AC133 epitope expressed on the CD133 glycoprotein has been widely used as a cell
surface marker of numerous stem cell and cancer stem cell types. It has been recently …

The putative tumor stem cell marker CD133 is the marker of choice for identifying brain
tumor stem cells in gliomas, but the use of different CD133 antibody clones possibly …