Supply and demand for endocannabinoids
BE Alger, J Kim - Trends in neurosciences, 2011 - cell.com
The endocannabinoid system consists of G-protein-coupled cannabinoid receptors that can
be activated by cannabis-derived drugs and small lipids termed endocannabinoids (eCBs) …
be activated by cannabis-derived drugs and small lipids termed endocannabinoids (eCBs) …
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain
Cannabis is the most commonly used illicit substance among pregnant women. Human
epidemiological and animal studies have found that prenatal cannabis exposure influences …
epidemiological and animal studies have found that prenatal cannabis exposure influences …
Brain cannabinoid CB2 receptors modulate cocaine's actions in mice
The presence and function of cannabinoid CB2 receptors in the brain have been the
subjects of much debate. We found that systemic, intranasal or intra-accumbens local …
subjects of much debate. We found that systemic, intranasal or intra-accumbens local …
Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice
A Ortega-Alvaro, A Aracil-Fernández… - …, 2011 - nature.com
The possible role of the CB 2 receptor (CB 2 r) in psychiatric disorders has been considered.
Several animal models use knockout (KO) mice that display schizophrenia-like behaviors …
Several animal models use knockout (KO) mice that display schizophrenia-like behaviors …
Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors
A Serrano, LH Parsons - Pharmacology & therapeutics, 2011 - Elsevier
The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …
Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight
V Di Marzo - Nature neuroscience, 2011 - nature.com
Studies of the endocannabinoid system in the CNS have been mostly focused on
endocannabinoid receptors and inactivating mechanisms. Until recently, very little was …
endocannabinoid receptors and inactivating mechanisms. Until recently, very little was …
The multiplicity of action of cannabinoids: implications for treating neurodegeneration
A Gowran, J Noonan… - CNS neuroscience & …, 2011 - Wiley Online Library
The cannabinoid (CB) system is widespread in the central nervous system and is crucial for
controlling a range of neurophysiological processes such as pain, appetite, and cognition …
controlling a range of neurophysiological processes such as pain, appetite, and cognition …
Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways
O Gomez, A Sanchez‐Rodriguez… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE The endogenous cannabinoid system participates in
oligodendrocyte progenitor differentiation in vitro. To determine the effect of synthetic …
oligodendrocyte progenitor differentiation in vitro. To determine the effect of synthetic …
Endocannabinoid-mediated synaptic plasticity and addiction-related behavior
N Sidhpura, LH Parsons - Neuropharmacology, 2011 - Elsevier
Endogenous cannabinoids (eCBs) are retrograde messengers that provide feedback
inhibition of both excitatory and inhibitory transmission in brain through the activation of …
inhibition of both excitatory and inhibitory transmission in brain through the activation of …
Molecular model of cannabis sensitivity in developing neuronal circuits
Prenatal cannabis exposure can complicate in utero development of the nervous system.
Cannabis impacts the formation and functions of neuronal circuitries by targeting …
Cannabis impacts the formation and functions of neuronal circuitries by targeting …