Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially Omega‐3 fatty acids
J Jerosch - International journal of rheumatology, 2011 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease that is characterized by increasing loss of
cartilage, remodeling of the periarticular bone, and inflammation of the synovial membrane …
cartilage, remodeling of the periarticular bone, and inflammation of the synovial membrane …
IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway
Objective Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the
pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the …
pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the …
Interaction of p53 with tumor suppressive and oncogenic signaling pathways to control cellular reactive oxygen species production
MF Ladelfa, MF Toledo, JE Laiseca… - Antioxidants & redox …, 2011 - liebertpub.com
Abstract p53 is a crucial transcription factor with tumor suppressive properties that elicits its
function through specific target genes. It constitutes a pivotal system that integrates …
function through specific target genes. It constitutes a pivotal system that integrates …
Rose hip and its constituent galactolipids confer cartilage protection by modulating cytokine, and chemokine expression
J Schwager, U Hoeller, S Wolfram… - BMC complementary and …, 2011 - Springer
Background Clinical studies have shown that rose hip powder (RHP) alleviates osteoarthritis
(OA). This might be due to anti-inflammatory and cartilage-protective properties of the …
(OA). This might be due to anti-inflammatory and cartilage-protective properties of the …
Apoptosis signaling kinases: from stress response to health outcomes
K Takeda, I Naguro, H Nishitoh… - Antioxidants & redox …, 2011 - liebertpub.com
Apoptosis is a highly regulated process essential for the development and homeostasis of
multicellular organisms. Whereas caspases, a large family of intracellular cysteine …
multicellular organisms. Whereas caspases, a large family of intracellular cysteine …
Phosphorylation and cytoplasmic localization of MAPK p38 during apoptosis signaling in bone marrow granulocytes of mice irradiated in vivo and the role of …
HRC Segreto, CTF Oshima, MF Franco, MRR Silva… - Acta histochemica, 2011 - Elsevier
We studied p38 phosphorylation and its intracellular localization during p53 and Puma (a
p53 upregulated modulator of apoptosis) apoptotic signaling pathway in bone marrow …
p53 upregulated modulator of apoptosis) apoptotic signaling pathway in bone marrow …
c-Jun N-terminal kinase and nuclear factor κB mediate nitric oxide-induced expression of matrix metalloproteinase-13
L Yang, A Guo, JC Gu - International orthopaedics, 2011 - Springer
The purpose of this study was to investigate the mechanism of expression of matrix
metalloproteinase-13 (MMP-13) induced by nitric oxide (NO). Human chondrocytes (HCs) …
metalloproteinase-13 (MMP-13) induced by nitric oxide (NO). Human chondrocytes (HCs) …
[PDF][PDF] IGF-1 and PDGF-bb Suppress IL-1b-Induced Cartilage Degradation through Down-Regulation of NF-kB Signaling: Involvement of Src/PI-3K/AKT Pathway
A Montaseri, F Busch, A Mobasheri… - PLoS …, 2011 - pdfs.semanticscholar.org
Abstract Objective: Interleukin-1b (IL-1b) is a pro-inflammatory cytokine that plays a key role
in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the …
in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the …
[PDF][PDF] Retinoic acid potentiates nitric oxide-induced dedifferentiation through the ERK pathway in rabbit articular chondrocytes
SM Yu, SJ Kim - Journal of Life Science, 2011 - Citeseer
Retinoic acid (RA), a metabolite of vitamin A, is known to regulate dedifferentiation of rabbit
articular chondrocytes. The regulatory mechanism of dedifferentiation by RA is not yet …
articular chondrocytes. The regulatory mechanism of dedifferentiation by RA is not yet …