The endocannabinoid system (ECS) is a signalling cascade consisting of CB1 and CB2
receptors, and enzymes for the synthesis and degradation of endogenous ligands for these …

The prohibition on use of cannabinoids in sporting competitions has been widely debated
and continues to be a contentious issue. Information continues to accumulate on the …

CB2 is a Gi protein–coupled receptor activated by endo‐and phytocannabinoids, thus
inhibiting stimulated adenylyl cyclase activity. CB2 is expressed in bone cells and Cb2 null …

Cannabinoid receptor 2 (CB2) plays an important role in human physiology and the
pathophysiology of different diseases, including neuroinflammation, neurodegeneration …

The herb Cannabis sativa (C. sativa) has been used in China and on the Indian
subcontinent for thousands of years as a medicine. However, since it was brought to the UK …

Cannabinoids are the active chemical components of Cannabis sativa (marijuana). The
medical use of cannabis goes back over 5,000 years. Cannabinoids produce a very wide …

Background: Both T-type calcium channels and cannabinoid receptors modulate signalling
in the primary afferent pain pathway. Here, we investigate the analgesics activities of a …

This research examines the in vitro interaction of phthalate diesters and monoesters with the
G protein-coupled cannabinoid 1 (CB1) receptor, a presynaptic complex involved in the …

The aim of this study was to determine the effect of WIN 55,212-2 mesylate (WIN—a non-
selective cannabinoid CB1 and CB2 receptor agonist) on the protective action of four …

We investigated the effects of cannabinoid receptor agonists on (1) oral cancer cell viability
in vitro and (2) oral cancer pain and tumor growth in a mouse cancer model. We utilized …