Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

The final step of biomineralization is a chemical precipitation reaction that occurs
spontaneously in supersaturated or metastable salt solutions. Genetic programs direct …

The mechanisms for vascular calcification and its associated cardiovascular mortality in
patients with ESRD are not completely understood. Dialysis patients exhibit profound …

Sixty-six years have elapsed since the discovery of fetuin in 1944, but its importance in
mammalian physiology has only recently been appreciated. Fetuin, first isolated from fetal …

Background A liver-derived protein, fetuin-A, was first purified from calf fetal serum in 1944,
but its potential role in lethal systemic inflammation was previously unknown. This study …

Background. Previous studies have shown that simple imaging methods may be useful for
detection of vascular calcifications in dialysis patients. Based on annual, plain chest X-rays …

Accelerated atherosclerotic plaque calcification and extensive medial calcifications are
common and highly detrimental complications of chronic kidney disease. Valid murine …

Background Previous studies have demonstrated that fetuin-A is related to insulin resistance
among subjects with normal glucose tolerance but not patients with type 2 diabetes. There …

Strong and unidirectional associations exist between the severity of cardiovascular
calcifications and mortality in patients with advanced chronic kidney disease. In the past 10 …

OBJECTIVE: Fetuin-A is an important player in the enhancement of insulin resistance. We
aimed to investigate the association of serum fetuin-A and metabolic syndrome (MetS) in a …