Congenital heart disease is the most common congenital disorder in newborns. Advances in
cardiovascular medicine and surgery have enabled most patients to reach adulthood …

Secundum-type atrial septal defects (ASDII) account for approximately 10% of all congenital
heart defects (CHD) and are associated with a familial risk. Mutations in transcription factors …

Objectives. To evaluate the recurrence of congenital heart disease (CHD) in pregnant
women with familial risk who had been referred for fetal echocardiography. Material and …

Abstract Background Tetralogy of Fallot (TOF) is the most commonly observed conotruncal
congenital heart defect. Treatment of these patients has evolved dramatically in the last few …

New discoveries using high-resolution methods for detecting genetic aberrations indicate
that the genetic contribution to congenital heart disease has been significantly …

The majority of congenital heart disease (CHD) occurs as a sporadic finding, with a minority
of cases associated with a known genetic abnormality. Combinations of genetic and …

Background: As a key enzyme in folate metabolism, 5, 10-methylenetetrahydrofolate
reductase (MTHFR) regulates the homeostasis between DNA synthesis and methylation …

Ventricular septal defect (VSD) is the most comon form of congenital heart disease (CHD).
DNA hypermethylation analysis may provide an insight into the molecular features and …

The 22. q11. 2 deletion syndrome (22q11DS) is a common genetic condition associated with
22q11. 2 microdeletions and classically has included congenital heart disease (CHD) as a …

All cardiologists will be called on to assess and manage pregnant women, however the
majority have had little or no training in the subject. In the same way, obstetricians assess …