Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

AA Gouw, A Seewann, WM Van Der Flier… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background White matter hyperintensities (WMH), lacunes and microbleeds are regarded as
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …

A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease

CE Sexton, UG Kalu, N Filippini, CE Mackay… - Neurobiology of …, 2011 - Elsevier
We reviewed case-control studies of diffusion tensor imaging (DTI) in patients with
Alzheimer's dementia (AD) and mild cognitive impairment (MCI), in order to establish the …

Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder

MJ Kempton, Z Salvador, MR Munafò… - Archives of general …, 2011 - jamanetwork.com
Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

B Mollenhauer, JJ Locascio… - The Lancet …, 2011 - thelancet.com
Background Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
are brain disorders characterised by intracellular α-synuclein deposits. We aimed to assess …

Heterogeneity in age-related white matter changes

R Schmidt, H Schmidt, J Haybaeck, M Loitfelder… - Acta …, 2011 - Springer
White matter changes occur endemically in routine magnetic resonance imaging (MRI)
scans of elderly persons. MRI appearance and histopathological correlates of white matter …

2001–2011: a decade of the LADIS (Leukoaraiosis And DISability) Study: what have we learned about white matter changes and small-vessel disease?

LADIS Study Group - Cerebrovascular diseases, 2011 - karger.com
Over the last 20 years, evidence about the clinical correlates of cerebral white matter
changes (WMC; also called leukoaraiosis) has been accumulating. WMC are now listed …

White matter lesions in Parkinson disease

NI Bohnen, RL Albin - Nature Reviews Neurology, 2011 - nature.com
Pure vascular parkinsonism without evidence of nigral Lewy body pathology may occur as a
distinct clinicopathological entity, but a much more frequent occurrence is the comorbid …

Effects of age and gender on white matter integrity

S Inano, H Takao, N Hayashi, O Abe… - American Journal of …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: DTI provides a sensitive measure of change in the
microstructure of white matter integrity. The purpose of our study was to investigate age …

Egocentric and allocentric memory as assessed by virtual reality in individuals with amnestic mild cognitive impairment

G Weniger, M Ruhleder, C Lange, S Wolf, E Irle - Neuropsychologia, 2011 - Elsevier
Present evidence suggests that medial temporal cortices subserve allocentric representation
and memory, whereas egocentric representation and memory also depends on parietal …

Brain aging, cognition in youth and old age and vascular disease in the Lothian Birth Cohort 1936: rationale, design and methodology of the imaging protocol

JM Wardlaw, ME Bastin… - … Journal of Stroke, 2011 - journals.sagepub.com
Rationale As the population of the world ages, age-related cognitive decline is becoming an
ever-increasing problem. However, the changes in brain structure that accompany normal …