Genetic vaccination for re-establishing T-cell tolerance in type 1 diabetes
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease resulting in the destruction
of the insulin-secreting β cells. Currently, there is no established clinical approach to …
of the insulin-secreting β cells. Currently, there is no established clinical approach to …
Polymeric gene delivery for diabetic treatment
SW Kim - Diabetes & Metabolism Journal, 2011 - synapse.koreamed.org
Several polymers were used to delivery genes to diabetic animals. Polyaminobutyl glycolic
acid was utilized to deliver IL-10 plasmid DNA to prevent autoimmune insulitis of non-obese …
acid was utilized to deliver IL-10 plasmid DNA to prevent autoimmune insulitis of non-obese …
Gene delivery using chemical methods
J Lalani, A Misra - Challenges in delivery of therapeutic genomics and …, 2011 - Elsevier
Publisher Summary This chapter elaborates the structure, function, and mechanism of
various polymeric vectors and their applicability in gene delivery. Polymers play a vital role …
various polymeric vectors and their applicability in gene delivery. Polymers play a vital role …
Herbal flavonoids inhibit the development of autoimmune diabetes in NOD mice: proposed mechanisms of action in the example of PADMA 28
L Weiss, V Barak, I Raz, R Or, S Slavin… - Alternative medicine …, 2011 - pagepress.org
Padma 28 is a multicompound herbal preparation based on the camphor formulas from
traditional tibetan medicine (TTM). It contains a variety of different secondary plant …
traditional tibetan medicine (TTM). It contains a variety of different secondary plant …
Autoimmunity and immunotherapy of type 1 Diabetes
M Aribi - Type 1 Diabetes-Pathogenesis, Genetics and …, 2011 - books.google.com
Type 1 diabetes, formerly termed insulin-dependent diabetes mellitus (IDDM), is a chronic
organ-specific autoimmune disorder thought to be caused by proinflammatory autoreactive …
organ-specific autoimmune disorder thought to be caused by proinflammatory autoreactive …
Non-viral gene therapy
J Zhang, X Li, L Lou, X Li, Y Jia, Z Jin, Y Zhu - … delivery: fundamentals and …, 2011 - Springer
Gene therapy has been considered to be a powerful approach for the prevention and/or
treatment of a variety of diseases from genetic disorders, infections, to cancer. The success …
treatment of a variety of diseases from genetic disorders, infections, to cancer. The success …
L-Arginine And L-Phenylalanine Based Poly (Ester Amide) S, Their Synthesis, Characterization, Formulations And Applications As Gene Delivery Vectors And Tissue …
J Wu - 2011 - ecommons.cornell.edu
A family of water soluble and positively charged L-arginine based poly (ester amide) s (Arg-
PEAs) was synthesized by solution polycondensation. These biodegradable Arg-PEAs …
PEAs) was synthesized by solution polycondensation. These biodegradable Arg-PEAs …