Myostatin is a member of the transforming growth factor-beta/bone morphogenetic protein
(TGF-β/BMP) super-family of secreted factors that functions as a potent inhibitor of skeletal …

Previously, we reported that administration of prolactin (PRL) during the early luteal phase in
sows increases plasma progesterone concentrations. In the current study, we searched for …

X-linked myotubular myopathy (XLMTM) is a congenital disorder caused by deficiency of the
lipid phosphatase, myotubularin. Patients with XLMTM often have severe perinatal …

Counteracting the atrophy of skeletal muscle associated with disuse has significant
implications for minimizing the wasting and weakness in plaster casting, joint immobilization …

Arthritis is a chronic inflammatory illness that induces cachexia, which has a direct impact on
morbidity and mortality. Fenofibrate, a selective PPARα activator prescribed to treat human …

Progesterone (P 4) secreted by the corpus luteum (CL) is critical for in utero embryo survival
and development, although CL proteins are key regulatory factors during the luteal phase …

Myostatin negatively regulates skeletal muscle growth. It was found that active immunization
with myostatin-specific vaccine blocked myostatin function in vivo, which resulted in increase …

Background Myostatin (MSTN) is a member of the transforming growth factor-ß superfamily
that functions as a negative regulator of skeletal muscle development and growth in …

Myostatin is a member of the transforming growth factor-β (TGF-β) super-family and
functions as a negative regulator of muscle growth. Binding of the specific receptor, Activin …

Small interfering RNA (siRNA)‐mediated silencing of gene expression is rapidly becoming a
powerful tool for molecular therapy. However, the rapid degradation of siRNAs and their …