Opiate versus psychostimulant addiction: the differences do matter
The publication of the psychomotor stimulant theory of addiction in 1987 and the finding that
addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 …
addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 …
[HTML][HTML] Impact of sex and gonadal hormones on cocaine and food reinforcement paradigms
KA Kerstetter, TE Kippin - Journal of addiction research & therapy, 2011 - ncbi.nlm.nih.gov
Men and women express sexually dimorphic patterns of cocaine abuse, such that women
progress faster from initially trying cocaine to becoming dependent upon the drug and …
progress faster from initially trying cocaine to becoming dependent upon the drug and …
Sensitivity to rewarding or aversive effects of methamphetamine determines methamphetamine intake
S Shabani, CS McKinnon, C Reed… - Genes, Brain and …, 2011 - Wiley Online Library
Amphetamines have rewarding and aversive effects. Relative sensitivity to these effects may
be a better predictor of vulnerability to addiction than sensitivity to one of these effects alone …
be a better predictor of vulnerability to addiction than sensitivity to one of these effects alone …
Effects of lidocaine-induced inactivation of the bed nucleus of the stria terminalis, the central or the basolateral nucleus of the amygdala on the opponent-process …
Rationale In addition to its rewarding actions, cocaine has profound negative effects that are
unmasked as the rewarding impact of the drug fades. While much is known about the …
unmasked as the rewarding impact of the drug fades. While much is known about the …
The interplay between brain 5-hydroxytryptamine levels and cocaine addiction
LJP Nonkes, IPG Van Bussel… - Behavioural …, 2011 - journals.lww.com
Cocaine addiction is a major health problem that affects millions of people. Cocaine acts by
inhibiting dopamine, noradrenaline and serotonin [5-hydroxytryptamine (5-HT)] reuptake …
inhibiting dopamine, noradrenaline and serotonin [5-hydroxytryptamine (5-HT)] reuptake …
Inactivation of the dorsal raphe nucleus reduces the anxiogenic response of rats running an alley for intravenous cocaine
A Ettenberg, OA Ofer, CL Mueller, S Waldroup… - Pharmacology …, 2011 - Elsevier
Rats traversing a straight alley once a day for delivery of a single iv injection of cocaine
develop over trials an ambivalence about entering the goal box. This ambivalence is …
develop over trials an ambivalence about entering the goal box. This ambivalence is …
Comparison of self-administration behavior and responsiveness to drug-paired cues in rats running an alley for intravenous heroin and cocaine
ZI Su, J Wenzel, R Baird, A Ettenberg - Psychopharmacology, 2011 - Springer
Rationale Evidence suggests that responsiveness to a drug-paired cue is predicted by the
reinforcing magnitude of the drug during prior self-administration. It remains unclear …
reinforcing magnitude of the drug during prior self-administration. It remains unclear …
Stimulant self-administration
LV Panlilio - Animal models of drug addiction, 2011 - Springer
Stimulants such as cocaine and the amphetamines are widely abused due to their
rewarding effects. Much of what we know about drug abuse and drug reward comes from …
rewarding effects. Much of what we know about drug abuse and drug reward comes from …
Dopamine and Norepinephrine Transporter Inhibition in Cocaine Addiction: Using Mice Expressing Cocaine-Insensitive Transporters
BJ Martin - 2011 - rave.ohiolink.edu
Cocaine's effects are predominately mediated by inhibiting the reuptake transporters for
dopamine, serotonin, and norepinephrine. How each of these transporters contributes to …
dopamine, serotonin, and norepinephrine. How each of these transporters contributes to …
Affective responses in cocaine-experienced rats reveal cue-induced drug craving and cocaine reward magnitude
EY Maier - 2011 - repositories.lib.utexas.edu
The development and persistence of cocaine dependence are greatly influenced by
emotional affect and cocaine associative learning. Cocaine is known to enhance nucleus …
emotional affect and cocaine associative learning. Cocaine is known to enhance nucleus …