Vascularization is the key challenge in tissue engineering

EC Novosel, C Kleinhans, PJ Kluger - Advanced drug delivery reviews, 2011 - Elsevier
The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …

Modulation of cell adhesion, proliferation and differentiation on materials designed for body implants

L Bacakova, E Filova, M Parizek, T Ruml… - Biotechnology …, 2011 - Elsevier
The interaction of cells and tissues with artificial materials designed for applications in
biotechnologies and in medicine is governed by the physical and chemical properties of the …

Comparison of different tissue-derived stem cell sheets for periodontal regeneration in a canine 1-wall defect model

Y Tsumanuma, T Iwata, K Washio, T Yoshida… - Biomaterials, 2011 - Elsevier
Cytotherapeutic approaches have been investigated to overcome the limitations of existing
procedures for periodontal regeneration. In this study, cell sheet transplantation was …

Cardiac cell sheet transplantation improves damaged heart function via superior cell survival in comparison with dissociated cell injection

H Sekine, T Shimizu, I Dobashi, K Matsuura… - … Engineering Part A, 2011 - liebertpub.com
Regenerative therapies have currently emerged as one of the most promising treatments for
repair of the damaged heart. Recently, numerous researchers reported that isolated cell …

Regenerative medicine as applied to solid organ transplantation: current status and future challenges

G Orlando, P Baptista, M Birchall… - Transplant …, 2011 - Wiley Online Library
In the last two decades, regenerative medicine has shown the potential for “bench‐to‐
bedside” translational research in specific clinical settings. Progress made in cell and stem …

[PDF][PDF] Current and future periodontal tissue engineering

Y Izumi, A Aoki, Y Yamada, H Kobayashi… - Periodontology …, 2011 - academia.edu
Periodontitis is an inflammatory disease that leads to the loss of tooth-supporting tissues.
Conventional periodontal treatment is generally unable to promote regeneration of the …

An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium

Y Liang, W Liu, B Han, C Yang, Q Ma, F Song… - Colloids and Surfaces B …, 2011 - Elsevier
Biodegradable hydrogels are important biomaterials for tissue engineering and drug
delivery. For the purpose of corneal regenerative medicine, we describe an in situ formed …

Fabrication and characters of a corneal endothelial cells scaffold based on chitosan

Y Liang, W Liu, B Han, C Yang, Q Ma, W Zhao… - Journal of Materials …, 2011 - Springer
A novel chitosan-based membrane that made of hydroxyethyl chitosan, gelatin and
chondroitin sulfate was used as a carrier of corneal endothelial cells. The characteristics of …

Tissue engineering using magnetite nanoparticles

A Ito, M Kamihira - Progress in molecular biology and translational …, 2011 - Elsevier
The major advantage of magnetic manipulation is “remote control.” Magnetic labeling of
cells with magnetic nanoparticles enables the manipulation of cells and also the control of …

pH-controlled recovery of placenta-derived mesenchymal stem cell sheets

O Guillaume-Gentil, OV Semenov, AH Zisch… - Biomaterials, 2011 - Elsevier
Widely used in different biomedical applications, polyelectrolyte multilayers provide inter alia
an attractive way for manufacturing of bio-functionalized, stimuli responsive surface coatings …