Dendritic spine pathology in neuropsychiatric disorders
Substantial progress has been made toward understanding the genetic architecture, cellular
substrates, brain circuits and endophenotypic profiles of neuropsychiatric disorders …
substrates, brain circuits and endophenotypic profiles of neuropsychiatric disorders …
MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Oscillations and hippocampal–prefrontal synchrony
LL Colgin - Current opinion in neurobiology, 2011 - Elsevier
The hippocampus, a structure required for many types of memory, connects to the medial
prefrontal cortex, an area that helps direct neuronal information streams during intentional …
prefrontal cortex, an area that helps direct neuronal information streams during intentional …
Dosage-dependent phenotypes in models of 16p11. 2 lesions found in autism
Recurrent copy number variations (CNVs) of human 16p11. 2 have been associated with a
variety of developmental/neurocognitive syndromes. In particular, deletion of 16p11. 2 is …
variety of developmental/neurocognitive syndromes. In particular, deletion of 16p11. 2 is …
Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder
MP Moreau, SE Bruse, R David-Rus, S Buyske… - Biological …, 2011 - Elsevier
BACKGROUND: MicroRNAs (miRNAs) are potent regulators of gene expression with
proposed roles in brain development and function. We hypothesized that miRNA expression …
proposed roles in brain development and function. We hypothesized that miRNA expression …
NeurimmiRs: microRNAs in the neuroimmune interface
Recent reports of microRNA (miR) modulators of both neuronal and immune processes
(here termed NeurimmiRs) predict therapeutic potential for manipulating NeurimmiR levels …
(here termed NeurimmiRs) predict therapeutic potential for manipulating NeurimmiR levels …
Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex
K Fénelon, J Mukai, B Xu, PK Hsu… - Proceedings of the …, 2011 - National Acad Sciences
Individuals with 22q11. 2 microdeletions have cognitive and behavioral impairments and the
highest known genetic risk for developing schizophrenia. One gene disrupted by the 22q11 …
highest known genetic risk for developing schizophrenia. One gene disrupted by the 22q11 …
Biogenesis and regulation of cardiovascular microRNAs
J Bauersachs, T Thum - Circulation research, 2011 - Am Heart Assoc
MicroRNAs (miRNAs) are important regulators of gene expression and fundamentally
impact on cardiovascular function in health and disease. A tight control of miRNA expression …
impact on cardiovascular function in health and disease. A tight control of miRNA expression …
microRNAs in neurons: manifold regulatory roles at the synapse
G Siegel, R Saba, G Schratt - Current opinion in genetics & development, 2011 - Elsevier
The regulation of synapse formation and plasticity in the developing and adult brain
underlies a complex interplay of intrinsic genetic programs and extrinsic factors. Recent …
underlies a complex interplay of intrinsic genetic programs and extrinsic factors. Recent …
Functions of noncoding RNAs in neural development and neurological diseases
S Bian, T Sun - Molecular neurobiology, 2011 - Springer
The development of the central nervous system (CNS) relies on precisely orchestrated gene
expression regulation. Dysregulation of both genetic and environmental factors can affect …
expression regulation. Dysregulation of both genetic and environmental factors can affect …