Osteoarthritis: an update with relevance for clinical practice

JWJ Bijlsma, F Berenbaum, FPJG Lafeber - The Lancet, 2011 - thelancet.com
Osteoarthritis is thought to be the most prevalent chronic joint disease. The incidence of
osteoarthritis is rising because of the ageing population and the epidemic of obesity. Pain …

Effects of glucosamine and chondroitin sulfate on cartilage metabolism in OA: outlook on other nutrient partners especially Omega‐3 fatty acids

J Jerosch - International journal of rheumatology, 2011 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease that is characterized by increasing loss of
cartilage, remodeling of the periarticular bone, and inflammation of the synovial membrane …

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy …

LM Wildi, JP Raynauld, J Martel-Pelletier… - Annals of the …, 2011 - ard.bmj.com
Objective To determine the effect of chondroitin sulphate (CS) treatment on cartilage volume
loss, subchondral bone marrow lesions (BML), synovitis and disease symptoms in patients …

Pharmacologic therapy for osteoarthritis—the era of disease modification

DJ Hunter - Nature Reviews Rheumatology, 2011 - nature.com
Osteoarthritis (OA) is a prevalent and disabling condition for which few safe and effective
therapeutic options are available. Current approaches are largely palliative and in an effort …

[HTML][HTML] Cartilage repair and joint preservation: medical and surgical treatment options

H Madry, UW Grün, G Knutsen - Deutsches Ärzteblatt International, 2011 - ncbi.nlm.nih.gov
Background Articular cartilage defects are most often caused by trauma and osteoarthritis
and less commonly by metabolic disorders of the subchondral bone, such as osteonecrosis …

Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study

EM Debbi, G Agar, G Fichman, YB Ziv… - … and Alternative Medicine, 2011 - Springer
Background Patients with osteoarthritis (OA) take a variety of health supplements in an
attempt to reduce pain and improve function. The aim of this study was to determine the …

New hope for the treatment of osteoarthritis through selective inhibition of MMP-13

NG Li, ZH Shi, YP Tang, ZJ Wang… - Current medicinal …, 2011 - ingentaconnect.com
Osteoarthritis (OA) is the leading cause of joint pain and disability in middle-aged and
elderly patients, and is characterized by progressive loss of articular cartilage that eventually …

Biochemical markers of ongoing joint damage in rheumatoid arthritis-current and future applications, limitations and opportunities

MA Karsdal, T Woodworth, K Henriksen… - Arthritis research & …, 2011 - Springer
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease associated with
potentially debilitating joint inflammation, as well as altered skeletal bone metabolism and …

[PDF][PDF] What is the effect of physical activity on the knee joint? A systematic review

DM Urquhart, JFL Tobing, FS Hanna… - Medicine & Science …, 2011 - researchgate.net
What Is the Effect of Physical Activity on the Knee Joint? A Systematic Review Page 1 What Is
the Effect of Physical Activity on the Knee Joint? A Systematic Review DONNA M. URQUHART1 …

[HTML][HTML] Complementary and alternative medicine

HT Debas, R Laxminarayan, SE Straus - 2011 - europepmc.org
The objective of medicine is to address people's unavoidable needs for emotional and
physical healing. The discipline has evolved over millennia by drawing on the religious …