Human retrovirus HTLV-1: descriptive and molecular epidemiology, origin, evolution, diagnosis and associated diseases

A Gessain - Bulletin de la Societe de pathologie exotique, 2011 - Springer
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic human
retrovirus discovered in 1980. It is estimated that around 10–20 million people are infected …

Modulation of innate immune responses during human T-cell leukemia virus (HTLV-1) pathogenesis

S Olière, R Douville, A Sze, SM Belgnaoui… - Cytokine & growth factor …, 2011 - Elsevier
Infection with the Human T-cell Leukemia virus type I (HTLV-1) retrovirus results in a number
of diverse pathologies, including the aggressive, fatal T-cell malignancy adult T-cell …

Inhibition of cyclin‐dependent kinase 5 but not of glycogen synthase kinase 3‐β prevents neurite retraction and tau hyperphosphorylation caused by secretable …

H Maldonado, E Ramírez, E Utreras… - Journal of …, 2011 - Wiley Online Library
Human T‐cell leukemia virus type I (HTLV‐I)‐associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a neurodegenerative disease characterized by selective loss of …

HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications

LC Ndhlovu, FE Leal, AM Hasenkrug… - PLoS neglected …, 2011 - journals.plos.org
The T cell immunoglobulin mucin 3 (Tim-3) receptor is highly expressed on HIV-1-specific T
cells, rendering them partially “exhausted” and unable to contribute to the effective immune …

[PDF][PDF] Le rétrovirus humain oncogène HTLV-1: épidémiologie descriptive et moléculaire, origine, évolution et aspects diagnostiques et maladies associées

A Gessain - Bulletin de la Société de pathologie exotique, 2011 - pathexo.societe-mtsi.fr
Résumé Le rétrovirus HTLV-1 (Human T cell leukemia/lymphoma virus type 1) est le premier
rétrovirus oncogène découvert chez l'Homme. On estime qu'il infecte 10 à 20 millions de …

HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP): still an obscure disease

M Mainardi Pillat, M Evandro Bauer… - … System Agents in …, 2011 - ingentaconnect.com
Human T-cell leukemia virus type 1 (HTLV-1) is the ethiologic agent of the neurological
disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Although …

[HTML][HTML] HTLV-1 Tax Specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications

FE Leal, LC Ndhlovu, AM Hasenkrug, AR Jha… - Retrovirology, 2011 - Springer
Background Most patients with HTLV-1 infection are asymptomatic, however 3% of
individuals develop a progressive neurological disorder, HTLV-1 associated …

Host Immune System Abnormalities Among Patients with Human T-Lymphotropic Virus Type 1 (HTLV-1)-Associated Disorders

T Sato, N Araya, N Yagishita, H Ando… - T-Cell Leukemia, 2011 - books.google.com
Human T-cell lymphotropic virus type 1 (HTLV-1) is a human retrovirus that causes
persistent infection in the host. While most infected persons remain asymptomatic carriers …