[HTML][HTML] Organ-specific features of natural killer cells
Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the
earliest arrivals at target organs of disease. However, the role of NK cells in mounting …
earliest arrivals at target organs of disease. However, the role of NK cells in mounting …
Use of allogeneic NK cells for cancer immunotherapy
MA Geller, JS Miller - Immunotherapy, 2011 - Taylor & Francis
Controversy exists as to the role that the immune system plays in cancer therapy. While the
immune system has been proposed to scavenge the body to prevent microscopic …
immune system has been proposed to scavenge the body to prevent microscopic …
Interferon-α in acute myeloid leukemia: an old drug revisited
S Anguille, E Lion, Y Willemen, VFI Van Tendeloo… - Leukemia, 2011 - nature.com
Abstract Interferon-α (IFN-α), a type I IFN, is a well-known antitumoral agent. The
investigation of its clinical properties in acute myeloid leukemia (AML) has been prompted …
investigation of its clinical properties in acute myeloid leukemia (AML) has been prompted …
[HTML][HTML] Early Peritoneal Immune Response during Echinococcus granulosus Establishment Displays a Biphasic Behavior
G Mourglia-Ettlin, JM Marqués… - PLoS neglected …, 2011 - journals.plos.org
Background Cystic echinococcosis is a worldwide distributed helminth zoonosis caused by
the larval stage of Echinococcus granulosus. Human secondary cystic echinococcosis is …
the larval stage of Echinococcus granulosus. Human secondary cystic echinococcosis is …
Cell-to-cell contact with hepatitis C virus-infected cells reduces functional capacity of natural killer cells
JC Yoon, JB Lim, JH Park, JM Lee - Journal of virology, 2011 - Am Soc Microbiol
The distinct feature of hepatitis C virus (HCV) infection is a high incidence of chronicity. The
reason for chronic HCV infection has been actively investigated, and impairment of innate …
reason for chronic HCV infection has been actively investigated, and impairment of innate …
The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I: C) and murine autoimmune cholangitis
YM Ambrosini, GX Yang, W Zhang… - Clinical & …, 2011 - academic.oup.com
A void in understanding primary biliary cirrhosis (PBC) is the absence of appropriate animal
models. Our laboratory has studied a murine model of autoimmune cholangitis induced …
models. Our laboratory has studied a murine model of autoimmune cholangitis induced …
[HTML][HTML] Poly (I: C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC
E Lion, S Anguille, ZN Berneman, ELJM Smits… - PloS one, 2011 - journals.plos.org
α Active specific immunotherapy aims at stimulating the host's immune system to recognize
and eradicate malignant cells. The concomitant activation of dendritic cells (DC) and natural …
and eradicate malignant cells. The concomitant activation of dendritic cells (DC) and natural …
Insights into NK cell biology from human genetics and disease associations
Rare human primary immunodeficiency disorders with extreme susceptibility to infections in
infancy have provided important insights into immune function. Increasingly, however …
infancy have provided important insights into immune function. Increasingly, however …
Chronic alcohol consumption decreases the percentage and number of NK cells in the peripheral lymph nodes and exacerbates B16BL6 melanoma metastasis into …
H Zhang, Z Zhu, GG Meadows - Cellular immunology, 2011 - Elsevier
NK cells in the lymph nodes play important roles in inhibiting tumor metastasis into draining
lymph nodes. Previously, we reported that chronic alcohol consumption interferes with NK …
lymph nodes. Previously, we reported that chronic alcohol consumption interferes with NK …
Impaired IFN-γ production and proliferation of NK cells in multiple sclerosis
A Lünemann, B Tackenberg, T DeAngelis… - International …, 2011 - academic.oup.com
NK cells are multicompetent lymphocytes of the innate immune system with a central role in
host defense and immune regulation. Studies in experimental animal models of multiple …
host defense and immune regulation. Studies in experimental animal models of multiple …