Despite its relatively recent emergence over the past few decades, oral health-related
quality of life (OHRQoL) has important implications for the clinical practice of dentistry and …

The minimal important difference (MID) is a phrase with instant appeal in a field struggling to
interpret health-related quality of life and other patient-reported outcomes. The terminology …

Background Data are lacking on the efficacy and safety of a combination chemotherapy
regimen consisting of oxaliplatin, irinotecan, fluorouracil, and leucovorin (FOLFIRINOX) as …

Background The multitargeted tyrosine kinase inhibitor sunitinib has shown activity against
pancreatic neuroendocrine tumors in preclinical models and phase 1 and 2 trials. Methods …

Objective We combined anchor-and distribution-based methods to establish minimally
important differences (MIDs) for six Patient-Reported Outcomes Measurement Information …

Background Xerostomia is the most common late side-effect of radiotherapy to the head and
neck. Compared with conventional radiotherapy, intensity-modulated radiotherapy (IMRT) …

Evidence-Based Guidelines for Determination of Sample Size and Interpretation of the
European Organisation for the Research and Page 1 Evidence-Based Guidelines for …

PURPOSE: To perform a randomized trial comparing 70 and 80 Gy radiotherapy for prostate
cancer. PATIENTS AND METHODS: A total of 306 patients with localized prostate cancer …

Purpose There are scant data regarding the effects of prophylactic cranial irradiation (PCI)
on neurocognitive function (NCF) and quality of life (QOL). Radiation Therapy Oncology …

Background This review aims to assist cancer clinical researchers in choosing between the
two most widely used measures of cancer-specific health-related quality of life: the …