Culture of cells as three-dimensional (3D) aggregates can enhance in vitro tests for basic
biological research as well as for therapeutics development. Such 3D culture models …

There is an increasing role for positron emission tomography (PET) in oncology, particularly
as a component of early phase clinical trials. As a non‐invasive functional imaging modality …

In vitro 3D culture is an important model for tissues in vivo. Cells in different locations of 3D
tissues are physiologically different, because they are exposed to different concentrations of …

Mesenchymal stromal cells (MSC) can be isolated from adult tissues and induced to
differentiate into skeletal cells, such as osteoblasts, chondrocytes and adipocytes …

Three-dimensional (3D) cell cultures have increased complexity compared to simple
monolayer and suspension cultures, recapitulating the cellular architecture and molecular …

Proper cell–cell communication through physical contact is crucial for a range of
fundamental biological processes including, cell proliferation, migration, differentiation, and …

Abstract Development of methods for scalable biofabrication of uniformly sized tissue
spheroids is essential for tissue spheroid-based bioprinting of large size tissue and organ …

Screening for effective therapeutic agents from millions of drug candidates is costly, time
consuming, and often faces concerns due to the extensive use of animals. To improve cost …

Multi-cellular tumor spheroids (MCTSs) have been established as a 3D physiologically
relevant tumor model for drug testing in cancer research. However, it is difficult to control the …

Here, we present a novel and simple process of spheroid formation and in situ
encapsulation of the formed spheroid without intervention. A hemispherical …