Metabolic disorders have seen an increased prevalence in recent years in developed as
well as developing countries. While it is clear lifestyle choices and habits have contributed to …

Obesity and its associated comorbidities represent one of the biggest public health
challenges facing the world today. The heritability of body weight is high, and genetic …

The health consequences of in utero exposure to maternal obesity on future generations are
concerning because they contribute to increased rates of diabetes, cardiovascular disease …

Prepregnancy maternal obesity confers an increased risk of stillbirth, but the mechanisms
are unknown. Maternal obesity is associated with placental inflammation. We considered …

The incidence of obesity and overweight has reached epidemic proportions in the
developed world as well as in those countries transitioning to first world economies, and this …

Understanding of the importance of dietary fatty acids has grown beyond a simple source of
energy to complex roles in regulating gene expression and cell and intracellular …

The perinatal environment plays an important role in programming many aspects of
physiology and behavior including metabolism, body weight set point, energy balance …

Chronic feeding on high-calorie diets causes obesity and type 2 diabetes mellitus (T2DM),
illnesses that affect hundreds of millions. Thus, understanding the pathways protecting …

Non‐technical summary An excess production of liver glucose is common in patients with
diabetes, and animal studies show that female rats who consume a high‐fat diet during …

The intrauterine environment is a major contributor to normal physiological growth and
development of an individual. Disturbances at this critical time can affect the long-term …