Hyaluronic acid hydrogels for biomedical applications

JA Burdick, GD Prestwich - Advanced materials, 2011 - Wiley Online Library
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human
body, is crucial for many cellular and tissue functions and has been in clinical use for over …

Critical issues in tissue engineering: biomaterials, cell sources, angiogenesis, and drug delivery systems

H Naderi, MM Matin… - Journal of biomaterials …, 2011 - journals.sagepub.com
Tissue engineering is a newly emerging biomedical technology, which aids and increases
the repair and regeneration of deficient and injured tissues. It employs the principles from …

Diels− Alder click cross-linked hyaluronic acid hydrogels for tissue engineering

CM Nimmo, SC Owen, MS Shoichet - Biomacromolecules, 2011 - ACS Publications
Hyaluronic acid (HA) is a naturally occurring polymer that holds considerable promise for
tissue engineering applications. Current cross-linking chemistries often require a coupling …

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

B Ananthanarayanan, Y Kim, S Kumar - Biomaterials, 2011 - Elsevier
Glioblastoma multiforme (GBM) is a malignant brain tumor characterized by diffuse
infiltration of single cells into the brain parenchyma, which is a process that relies in part on …

Synthesis and characterization of tunable poly (ethylene glycol): gelatin methacrylate composite hydrogels

CB Hutson, JW Nichol, H Aubin, H Bae… - … Engineering Part A, 2011 - liebertpub.com
Poly (ethylene glycol)(PEG) hydrogels are popular for cell culture and tissue-engineering
applications because they are nontoxic and exhibit favorable hydration and nutrient …

Design of artificial extracellular matrices for tissue engineering

BS Kim, IK Park, T Hoshiba, HL Jiang, YJ Choi… - Progress in Polymer …, 2011 - Elsevier
The design of artificial extracellular matrix (ECM) is important in tissue engineering because
artificial ECM regulates cellular behaviors, including proliferation, survival, migration, and …

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels

Y Lei, S Gojgini, J Lam, T Segura - Biomaterials, 2011 - Elsevier
Synthetic hydrogel scaffolds that can be used as culture systems that mimic the natural stem
cell niche are of increased importance for stem cell biology and regenerative medicine …

Stem cells and cell therapies in lung biology and lung diseases

DJ Weiss, I Bertoncello, Z Borok, C Kim… - Proceedings of the …, 2011 - atsjournals.org
EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

Composite scaffold provides a cell delivery platform for cardiovascular repair

AFG Godier-Furnémont, TP Martens… - Proceedings of the …, 2011 - National Acad Sciences
Control over cell engraftment, survival, and function remains critical for heart repair. We have
established a tissue engineering platform for the delivery of human mesenchymal progenitor …

Stem cell cultivation in bioreactors

CAV Rodrigues, TG Fernandes, MM Diogo… - Biotechnology …, 2011 - Elsevier
Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …