Colorectal cancer is a complex disease resulting from somatic genetic and epigenetic
alterations, including locus-specific CpG island methylation and global DNA or LINE-1 …

Prediction of prognosis in colorectal cancer is vital for the choice of therapeutic options.
Histopathological factors remain paramount in this respect. Factors such as tumor size …

BACKGROUND & AIMS:: Colonoscopy screening might have greater protective effects for
prevention of distal than proximal colorectal cancer. Serrated polyps are frequently located …

The aim of this study was to relate the density of tumor infiltrating T cells to cancer-specific
survival in colorectal cancer, taking into consideration the CpG island methylator phenotype …

Colorectal cancer (CRC) is a heterogeneous disorder than arises via multiple distinct
pathways, such as the serrated pathway, in which serrated polyps (including variants of …

Abundant recent data suggest that sessile serrated adenoma/polyp (SSA/P) is an early
precursor lesion in the serrated pathway of carcinogenesis. It is believed that SSA/Ps …

Over the past two decades, several protein and genomic markers have refined the
prognostic information of colorectal cancer (CRC) and helped to predict which patient group …

BACKGROUND: Hyperplastic polyposis syndrome is a rare syndrome of colorectal cancer
predisposition. Patterns of inheritance of hyperplastic polyposis syndrome are not obvious …

Background Although sessile serrated adenomas (SSAs) may represent a separate and
important pathway for colorectal cancer (CRC), little is known about the risk factors for these …

Hyperplastic polyposis syndrome (HPS) is characterized by the presence of multiple
colorectal serrated polyps and is associated with an increased colorectal cancer (CRC) risk …