Cerebral autoregulation in Alzheimer's disease

JAHR Claassen, R Zhang - Journal of Cerebral Blood Flow & …, 2011 - journals.sagepub.com
Cerebral autoregulation aims to stabilize blood flow to the brain during variations in
perfusion pressure, thus protecting the brain against the risks of low or high systemic blood …

Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease

Y Chen, DA Wolk, JS Reddin, M Korczykowski… - Neurology, 2011 - AAN Enterprises
Objective: We compared the ability of arterial spin labeling (ASL), an MRI method that
measures cerebral blood flow (CBF), to that of FDG-PET in distinguishing patients with …

Regional brain atrophy and functional disconnection across Alzheimer's disease evolution

T Gili, M Cercignani, L Serra, R Perri… - Journal of Neurology …, 2011 - jnnp.bmj.com
Objective To assess the contribution of regional grey matter (GM) atrophy and functional
disconnection in determining the level of cognitive decline in patients with Alzheimer's …

Disconnection of frontal and parietal areas contributes to impaired attention in very early Alzheimer's disease

S Neufang, A Akhrif, V Riedl, H Förstl… - Journal of …, 2011 - content.iospress.com
In Alzheimer's disease (AD), the loss of cerebral connectivity has been evidenced by
numerous studies. There is growing evidence of attention related failures already in …

Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups—The AddNeuroMed study

Y Liu, T Paajanen, Y Zhang, E Westman… - Neurobiology of …, 2011 - Elsevier
To study the ability of neuropsychological tests, manual MRI hippocampal volume
measures, regional volume and cortical thickness measures to identify subjects with …

Staging neurodegenerative disorders: structural, regional, biomarker, and functional progressions

T Archer, RM Kostrzewa, RJ Beninger, T Palomo - Neurotoxicity research, 2011 - Springer
The notion of staging in the neurodegenerative disorders is modulated by the constant and
progressive loss of several aspects of brain structural integrity, circuitry, and neuronal …

Interpersonal traits change as a function of disease type and severity in degenerative brain diseases

M Sollberger, J Neuhaus, R Ketelle… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Different degenerative brain diseases result in distinct personality changes as a
result of divergent patterns of brain damage; however, little is known about the natural …

Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice

GL Poirier, E Amin, MA Good, JP Aggleton - Neuroscience, 2011 - Elsevier
A mouse model of amyloid pathology was used to first examine using a cross sectional
design changes in retrosplenial cortex activity in transgenic mice aged 5, 11, 17, and 23 …

Simultaneous arterial spin labeling cerebral blood flow and morphological assessments for detection of Alzheimer's disease

T Dashjamts, T Yoshiura, A Hiwatashi, K Yamashita… - Academic radiology, 2011 - Elsevier
RATIONALE AND OBJECTIVES: The relative roles of arterial spin-labeling (ASL) perfusion
imaging and magnetic resonance morphological assessment in diagnosing Alzheimer's …

Optimized Data Preprocessing for Multivariate Analysis Applied to 99mTc-ECD SPECT Data Sets of Alzheimer's Patients and Asymptomatic Controls

D Merhof, PJ Markiewicz, G Platsch… - Journal of Cerebral …, 2011 - journals.sagepub.com
Multivariate image analysis has shown potential for classification between Alzheimer's
disease (AD) patients and healthy controls with a high-diagnostic performance. As image …