Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

JW Kronstad, R Attarian, B Cadieux, J Choi… - Nature reviews …, 2011 - nature.com
Cryptococcus neoformans is generally considered to be an opportunistic fungal pathogen
because of its tendency to infect immunocompromised individuals, particularly those …

Sex in fungi

M Ni, M Feretzaki, S Sun, X Wang… - Annual review of …, 2011 - annualreviews.org
Sexual reproduction enables genetic exchange in eukaryotic organisms as diverse as fungi,
animals, plants, and ciliates. Given its ubiquity, sex is thought to have evolved once, possibly …

Evidence that the Human Pathogenic Fungus Cryptococcus neoformans var. grubii May Have Evolved in Africa

AP Litvintseva, I Carbone, J Rossouw, R Thakur… - PLoS …, 2011 - journals.plos.org
Most of the species of fungi that cause disease in mammals, including Cryptococcus
neoformans var. grubii (serotype A), are exogenous and non-contagious. Cryptococcus …

6 Mating type in basidiomycetes: unipolar, bipolar, and tetrapolar patterns of sexuality

U Kües, TY James, J Heitman - Evolution of fungi and fungal-like …, 2011 - Springer
We summarize current knowledge on the structure of mating type loci in different species of
basidiomycetes, giving special consideration to bipolar and tetrapolar heterothallic species …

Microbial pathogens in the fungal kingdom

J Heitman - Fungal biology reviews, 2011 - Elsevier
The fungal kingdom is vast, spanning∼ 1.5 to as many as 5 million species diverse as
unicellular yeasts, filamentous fungi, mushrooms, lichens, and both plant and animal …

Molecular analysis and mating behaviour of the Trichophyton mentagrophytes species complex

F Symoens, O Jousson, C Planard, M Fratti… - International Journal of …, 2011 - Elsevier
Isolates of the Trichophyton mentagrophytes complex vary phenotypically. Whether the
closely related zoophilic and anthropophilic anamorphs currently associated with …

The F-Box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans

TB Liu, Y Wang, S Stukes, Q Chen, A Casadevall… - Eukaryotic …, 2011 - Am Soc Microbiol
Cryptococcus neoformans is the leading cause of fungal meningitis in immunocomprised
populations. Although extensive studies have been conducted on signal transduction …

The cAMP/Protein Kinase A Pathway and Virulence in Cryptococcus neoformans

JW Kronstad, G Hu, J Choi - Mycobiology, 2011 - Taylor & Francis
The basidiomycete fungus Cryptococcus neoformans is an important pathogen of
immunocompromised people. The ability of the fungus to sense its environment is critical for …

Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway

KW Jung, SY Kim, LH Okagaki, K Nielsen… - Fungal Genetics and …, 2011 - Elsevier
The mitogen-activated protein kinase (MAPK) pathways control diverse cellular functions in
pathogenic fungi, including sexual differentiation, stress response, and maintenance of cell …