There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …

The diagnosis of neurodegenerative diseases within neurology and psychiatry are
hampered by the difficulty in getting biopsies and thereby validating the diagnosis by …

High exposure to vitamin D may protect against development and progression of multiple
sclerosis (MS), possibly through the immunomodulatory properties of its biologically active …

Background: Recent studies conducted in arthritis, asthma, and inflammatory bowel disease
suggest that chitinases are important in inflammatory processes and tissue remodeling …

As therapeutic options for multiple sclerosis widen, validated biomarkers of clinical disease
activity are urgently needed. Reliable biomarkers would assist in choosing initial therapy …

Nuclear factor I-X3 (NFI-X3) is a newly identified splice variant of NFI-X that regulates
expression of several astrocyte-specific markers, such as glial fibrillary acidic protein. Here …

Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous
system (CNS). A growing body of evidence supports a role for vitamin D in MS aetiology …

Following emerging evidence that neurodegenerative processes in multiple sclerosis (MS)
are present from its early stages, an intensive scientific interest has been directed to …

Although a small number of patients have slowly progressive neurologic deficits from the
onset of the disease (primary progressive multiple sclerosis [PPMS]), most (85%) experience …

Background: Metals are suspected of being involved in the pathogenesis of various
neurologic diseases. We previously found a complex imbalance in serum chemical …