[HTML][HTML] Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation

MP Kummer, M Hermes, A Delekarte… - Neuron, 2011 - cell.com
Part of the inflammatory response in Alzheimer's disease (AD) is the upregulation of the
inducible nitric oxide synthase (NOS2) resulting in increased NO production. NO contributes …

Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease

RM Liu, T Van Groen, A Katre, D Cao, I Kadisha… - Neurobiology of …, 2011 - Elsevier
Accumulation of amyloid beta peptide (Aβ) in the brain is a pathological hallmark of
Alzheimer's disease (AD); the underlying mechanism, however, is not well understood. In …

Diseases in pet degus: a retrospective study in 300 animals

V Jekl, K Hauptman, Z Knotek - Journal of Small Animal …, 2011 - Wiley Online Library
Introduction: Degus are commonly used as laboratory animals; however, over the past few
years, they have become increasingly popular as pets. Objectives: The aim of this article …

Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology

T van Groen, I Kadish, N Popović, M Popović… - Neurobiology of …, 2011 - Elsevier
Recently it has been shown that over 3-year-old wild-type South American rodents, Octodon
degus, the “common degu” or degu, of their own accord develop Alzheimer's disease …

Lesion-induced vertebrate models of Alzheimer dementia

A Toledano, MI Álvarez - Animal models of dementia, 2011 - Springer
No animal spontaneously suffers from Alzheimer's disease (AD), nor can it be
experimentally induced. However, there is a huge research need for models of AD. Lesion …

[图书][B] Automated behavioral phenotyping of inbred mouse strains and mouse models of Alzheimer disease

A Codita - 2011 - search.proquest.com
Behavioral characterization of various mouse strains created as models for human diseases
such as Alzheimer disease requires robust phenotyping methods. Previous work on inbred …