Although significant advances have recently been made in the understanding and treatment
of multiple sclerosis, reduction of long‐term disability remains a key goal. Evidence suggests …

Inflammation is an important pathogenic mechanism in many neurodegenerative disorders.
Activated microglia play a pivotal role in releasing pro-inflammatory factors including …

Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease with
characteristic foci of inflammatory demyelination in the brain, spinal cord, and optic nerves …

J. Neurochem.(2011) 118, 205–214. Abstract Experimental autoimmune encephalomyelitis
(EAE) is a model of multiple sclerosis. Dark Agouti rats immunized with spinal cord …

Peroxynitrite has been suggested to be the potent oxidant causing toxicity to neurons and
oligodendrocytes (OLs). Our previous studies have illustrated that intracellular zinc liberation …

We studied the products of nitrosative stress, immunoglobulins, and autoantibodies to
nitrated proteins in the liquor of patients during the first day after stroke onset. The level of …

Исследовано содержание продуктов нитрозативного стресса, иммуноглобулинов и
аутоантител к нитрованным белкам в ликворе больных в первые сутки после …

Abstract The etiology of Multiple Sclerosis (MS) is unknown, but is believed to involve three
factors (Table 3.1). The first is genetic vulnerability. Associated risk/susceptibility genes …

Numerous experimental data shows that mitochondrial dysfunction may play a key role in
neurodegenerative disorder. Mitochondria are the site of early damage in …