The double life of a B-1 cell: self-reactivity selects for protective effector functions
N Baumgarth - Nature Reviews Immunology, 2011 - nature.com
During their development, B and T cells with self-reactive antigen receptors are generally
deleted from the repertoire to avoid autoimmune diseases. Paradoxically, innate-like B-1 …
deleted from the repertoire to avoid autoimmune diseases. Paradoxically, innate-like B-1 …
Primary vitreoretinal lymphoma: a report from an international primary central nervous system lymphoma collaborative group symposium
CC Chan, JL Rubenstein, SE Coupland… - The …, 2011 - academic.oup.com
Primary vitreoretinal lymphoma (PVRL), also known as primary intraocular lymphoma, is a
rare malignancy typically classified as a diffuse large B‐cell lymphoma and most frequently …
rare malignancy typically classified as a diffuse large B‐cell lymphoma and most frequently …
IL-33 activates B1 cells and exacerbates contact sensitivity
M Komai-Koma, DS Gilchrist… - The Journal of …, 2011 - journals.aai.org
B1 B cells produce natural IgM and play a critical role in the early defense against bacterial
and viral infection. The polyreactive IgM also contributes to the clearance of apoptotic …
and viral infection. The polyreactive IgM also contributes to the clearance of apoptotic …
A critical role of IL-17 in modulating the B-cell response during H5N1 influenza virus infection
Abstract Interleukin-17 (IL-17), a member of the IL-17 cytokine family, plays a crucial role in
mediating the immune response against extracellular bacteria and fungi in the lung …
mediating the immune response against extracellular bacteria and fungi in the lung …
Macrophage heterogeneity and acute inflammation
K Liddiard, M Rosas, LC Davies… - European journal of …, 2011 - Wiley Online Library
In this Viewpoint, we concentrate on the aspects of macrophage biology that we believe are
fundamental for an appropriate contextual understanding of macrophage function during …
fundamental for an appropriate contextual understanding of macrophage function during …
Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice
CAH Hansell, C Schiering, R Kinstrie… - Blood, The Journal …, 2011 - ashpublications.org
Mouse innate-like B cells are a heterogeneous collection of multifunctional cells that control
infection, play housekeeping roles, contribute to adaptive immunity, and suppress …
infection, play housekeeping roles, contribute to adaptive immunity, and suppress …
The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system
EK Rainey-Barger, JM Rumble, SJ Lalor, N Esen… - Brain, behavior, and …, 2011 - Elsevier
Cases of progressive multifocal leukoencephalopathy can occur in patients treated with the
B cell depleting anti-CD20 antibody, rituximab, highlighting the importance of B cell …
B cell depleting anti-CD20 antibody, rituximab, highlighting the importance of B cell …
Characterization of immunostimulatory components of orf virus (parapoxvirus ovis)
A Friebe, S Friederichs, K Scholz… - Journal of general …, 2011 - microbiologyresearch.org
Inactivated orf virus (ORFV, parapoxvirus ovis) induces antiviral activity in animal models of
acute and chronic viral infections and exerts strong effects on human immune cells. ORFV …
acute and chronic viral infections and exerts strong effects on human immune cells. ORFV …
Resident peritoneal NK cells
R Gonzaga, P Matzinger… - The Journal of Immunology, 2011 - journals.aai.org
In this study, we describe a new population of NK cells that reside in the normal, uninflamed
peritoneal cavity. Phenotypically, they share some similarities with the small population of …
peritoneal cavity. Phenotypically, they share some similarities with the small population of …
Chemokines and their receptors in the allergic airway inflammatory process
JR Velazquez, LM Teran - Clinical reviews in allergy & immunology, 2011 - Springer
The development of the allergic airway disease conveys several cell types, such as T-cells,
eosinophils, mast cells, and dendritic cells, which act in a special and temporal …
eosinophils, mast cells, and dendritic cells, which act in a special and temporal …