Chlamydia trachomatis genital infection is a worldwide public health problem, and
considerable effort has been expended on developing an efficacious vaccine. The murine …

Infectious diseases represent a continuously growing menace that has severe impact on
health of the people worldwide, particularly in the developing countries. Therefore, novel …

Vaccine-preventable diseases are still responsible for the deaths of more than 1 million
children under the age of 5 years annually, mostly in developing countries. A substantial …

Traditional phosphodiester lipid vesicles (liposomes) are not stable and could be easily
degraded in the gastrointestinal (GI) tract. We prepared a novel lipid based oral delivery …

Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterial pathogen in
the World and there is an urgent need for a vaccine to prevent these infections. To determine …

The native major outer membrane protein (nMOMP) from Chlamydia was purified in its
trimeric form using the zwitterionic detergent Z3-14. In aliquots from this preparation, Z3-14 …

Whilst oral vaccination is a potentially preferred route in terms of patient adherence and
mass vaccination, the ability to formulate effective oral vaccines remains a challenge. The …

Immunization has been realized as one of the most cost effective methods of controlling
microbial infections. Currently, the most widely employed means of vaccine delivery …

Preclinical models of nicotine vaccine pharmacology have relied on iv or sc administration of
nicotine. Models using cigarette smoke inhalation might more accurately simulate nicotine …

Nasal vaccination is an effective therapeutic means of preventing upper respiratory infection.
Recently, nasal vaccination with P6 outer membrane protein of nontypeable Haemophilus …