Epigenetic marks such as posttranslational histone modifications specify the functional
states of underlying DNA sequences, though how they are maintained after their disruption …

Repeated cocaine exposure induces persistent alterations in genome-wide transcriptional
regulatory networks, chromatin remodeling activity and, ultimately, gene expression profiles …

The conventional view of Janus kinase 2 (JAK2) is a nonreceptor tyrosine kinase which
transmits information to the nucleus via the signal transducer and activator of transcriptions …

The genome is organised into large scale structures in the interphase nucleus.
Pericentromeric heterochromatin represents one such compartment characterised by …

Background Protein exchange kinetics correlate with the level of chromatin condensation
and, in many cases, with the level of transcription. We used fluorescence recovery after …

How the co-ordinated events of gene activation and silencing during cellular differentiation
are influenced by spatial organization of the cell nucleus is still poorly understood. Little is …

Here, we focus on epigenetic changes in leukaemia and MM (multiple myeloma) cells. We
show how the histone signature, DNA methylation and levels of select tumour‐suppressor …

Determining averaged effective diffusion constants from experimental measurements of
fluorescent proteins in an inhomogeneous medium in the presence of ligand-receptor …

We have studied JMJD2b histone demethylase, which antagonizes H3K9me3 in the
pericentromeric heterochromatin. In cells with a deficiency in the histone methyltransferase …

Aids has become the leading cause of death world-wide. Much research has been done on
the causal agent of this disease, the human immunodeficiency virus (HIV). HIV infection in …