The genetics of asthma and allergic disease: a 21st century perspective

C Ober, TC Yao - Immunological reviews, 2011 - Wiley Online Library
Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

Genome‐wide association studies for discovery of genes involved in asthma

L Akhabir, AJ Sandford - Respirology, 2011 - Wiley Online Library
Asthma is the result of a complex interaction between environmental factors and genetic
variants that confer susceptibility. Studies of the genetics of asthma have previously been …

[HTML][HTML] The genetics of asthma and allergic disorders

ME March, PMA Sleiman… - Discovery …, 2011 - discoverymedicine.com
Asthma and allergic diseases are complex conditions caused by a combination of genetic
and environmental factors. More than 100 genes have been associated with asthma and …

Genetic studies of the etiology of asthma

KC Barnes - Proceedings of the American Thoracic Society, 2011 - atsjournals.org
Asthma is a heterogeneous disease for which a strong genetic basis is firmly established.
Although the generally accepted definition includes three domains of symptoms (variable …

[HTML][HTML] The search for genetic variants and epigenetics related to asthma

SH Lee, JS Park, CS Park - Allergy, asthma & immunology …, 2011 - synapse.koreamed.org
For the past two decades, a huge number of genetic studies have been conducted to identify
the genetic variants responsible for asthma risk. Several types of genetic and genomic …

Role of ADAM33 gene and associated single nucleotide polymorphisms in asthma

N Sharma, P Tripathi, S Awasthi - Allergy & Rhinology, 2011 - journals.sagepub.com
Asthma is a multifactorial disorder, primarily resulting from interactions between genetic and
environmental factors. ADAM33 gene (located on chromosome 20p13) has been reported to …

The lung: the natural boundary between nature and nurture

MA Seibold, DA Schwartz - Annual review of physiology, 2011 - annualreviews.org
Common lung diseases such as asthma, COPD, and pulmonary fibrosis cause significant
morbidity and mortality in the US and worldwide. Research investigating the mechanisms of …

The use of automated parameter searches to improve ion channel kinetics for neural modeling

EB Hendrickson, JR Edgerton, D Jaeger - Journal of computational …, 2011 - Springer
The voltage and time dependence of ion channels can be regulated, notably by
phosphorylation, interaction with phospholipids, and binding to auxiliary subunits. Many …

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1)

RJ Holt, Y Zhang, A Binia, AL Dixon… - Journal of allergy and …, 2011 - Elsevier
BACKGROUND: Asthma is a common, chronic inflammatory airway disease of major public
health importance with multiple genetic determinants. Previously, we found by positional …

A clinical observation of Chungsangboha-tang's effects on asthmatic patients

JH Bang, HJ Jung - The Journal of Internal Korean Medicine, 2011 - koreascience.kr
Objectives: Asthma is considered an inflammation disease characterized by airway
hyperresponsiveness and pulmonary eosinophilia. Chungsang boha-tang is a herbal …