Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

JB Michel, JL Martin-Ventura, J Egido… - Cardiovascular …, 2011 - academic.oup.com
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of
atherothrombosis, providing a unique human model of this disease. The pathogenesis of …

Current status of medical management for abdominal aortic aneurysm

J Golledge, PE Norman - Atherosclerosis, 2011 - Elsevier
Previous trials indicate that surgical management of small abdominal aortic aneurysms
(AAA) does not reduce mortality. The medical management of AAA, however, has to a large …

Matrix metalloproteinases in tuberculosis

PT Elkington, CA Ugarte-Gil… - European respiratory …, 2011 - Eur Respiratory Soc
Tuberculosis (TB) remains a global health pandemic. Infection is spread by the aerosol route
and Mycobacterium tuberculosis must drive lung destruction to be transmitted to new hosts …

Porphyromonas gingivalis Participates in Pathogenesis of Human Abdominal Aortic Aneurysm by Neutrophil Activation. Proof of Concept in Rats

S Delbosc, JM Alsac, C Journe, L Louedec, Y Castier… - PLoS …, 2011 - journals.plos.org
Background Abdominal Aortic Aneurysms (AAAs) represent a particular form of
atherothrombosis where neutrophil proteolytic activity plays a major role. We postulated that …

Proteomic analysis of polymorphonuclear neutrophils identifies catalase as a novel biomarker of abdominal aortic aneurysm: potential implication of oxidative stress in …

P Ramos-Mozo, J Madrigal-Matute… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Polymorphonuclear neutrophils (PMNs) play a main role in abdominal aortic
aneurysm (AAA) progression. We have analyzed circulating PMNs isolated from AAA …

Vascular calcification and aortic fibrosis: a bifunctional role for osteopontin in diabetic arteriosclerosis

JS Shao, OL Sierra, R Cohen, RP Mecham… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Calcification and fibrosis reduce vascular compliance in arteriosclerosis. To
better understand the role of osteopontin (OPN), a multifunctional protein upregulated in …

[HTML][HTML] Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice

R Hashizume, A Yamawaki-Ogata, Y Ueda… - Journal of vascular …, 2011 - Elsevier
OBJECTIVE: Aortic aneurysm (AA) is associated with loss of elastin and structural integrity,
accompanied by increased matrix metalloproteinase (MMP) expression. These processes …

Doxycycline inhibition of abdominal aortic aneurysm growth-a systematic review of the literature

BR Dodd, RA Spence - Current vascular pharmacology, 2011 - ingentaconnect.com
Abdominal aortic aneurysm (AAA) is a common disease and a major cause of death through
rupture, the risk of which increases with aneurysm size. There is approximately a 5 year …

Doxycycline enhances the inhibitory effects of bevacizumab on corneal neovascularization and prevents its side effects

W Su, Z Li, Y Li, M Lin, L Yao, Y Liu… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To investigate the combination therapeutic effects of topical doxycycline
temperature-sensitive hydrogel (DTSH) and bevacizumab on corneal neovascularization …

Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix metalloproteinase‐2 induction

N Aoyama, J Suzuki, D Wang, M Ogawa… - Journal of …, 2011 - Wiley Online Library
Aoyama N, Suzuki J, Wang D, Ogawa M, Kobayashi N, Hanatani T, Takeuchi Y, Izumi Y,
Isobe M. Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix …