Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

In the search for specific genes regulated by DNA methylation in rheumatoid arthritis (RA),
we investigated the expression of CXCL12 in synovial fibroblasts (SFs) and the methylation …

In CXC chemokines, two conserved C residues are separated by one unconserved amino
acid. These mediators chemoattract neutrophils, lymphocytes and monocytes into the …

OBJECTIVES: CXCL12 is a constitutively expressed chemokine with important homeostatic
functions. Increased CXCL12 expression has been observed in several inflammatory …

Introduction IFN-gamma inducible protein-10 (CXCL10), a member of the CXC chemokine
family, and its receptor CXCR3 contribute to the recruitment of T cells from the blood stream …

The seven-spanning transmembrane G-protein coupled receptor CXCR4, which specifically
binds to the chemokine CXCL12, is expressed on many cell types, including various types of …

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease, which causes
synovial damage. Persistence of lymphocyte infiltrates in the rheumatoid synovium has been …

Chemokines produced by synoviocytes of the subacromial bursa are up‐regulated in
subacromial bursitis and rotator cuff disease. We hypothesized that SDF‐1α production in …

The chemokine receptor CXCR4 is a member of the seven transmembrane GPCR family,
which is implicated in multiple diseases, including HIV infection, cancers, and rheumatoid …

Objective. Plectranthus amboinicus has been known to treat inflammatory diseases or
swelling symptoms. We investigated whether P. amboinicus exhibited an inhibitory effect on …