Catalyst and solvent-free amidation of inactive esters of N-protected amino acids
A catalyst free procedure for the preparation of amides from inactive esters of N-protected
amino acids and various amines is demonstrated under mild reaction conditions. Our effort …
amino acids and various amines is demonstrated under mild reaction conditions. Our effort …
First, Second, and Third Generation Scalable Syntheses of Two Potent H3 Antagonists
DJ Pippel, JE Mills, CR Pandit, LK Young… - … Process Research & …, 2011 - ACS Publications
Our teams have recently completed scale-up campaigns for two structurally similar H3
receptor antagonists. The first and second generation processes were developed for the …
receptor antagonists. The first and second generation processes were developed for the …