The limiting factor for successful hematopoietic stem cell transplantation (HSCT) is graft-
versus-host disease (GvHD), a post-transplant disorder that results from immune-mediated …

Risk factors for grades 2-4 acute graft-versus-host disease (GVHD) and for chronic GVHD as
defined by National Institutes of Health consensus criteria were evaluated and compared in …

Allogeneic hematopoietic stem cell transplantation (HSCT) has been a curative therapeutic
option for a wide range of immune hematologic malignant and non‐malignant disorders …

Self/non‐self discrimination is a fundamental requirement of life. Endogenous peptides
presented by major histocompatibility complex class I (MHC I) molecules represent the …

Background While the role of canonical (β-catenin-mediated) Wnt signaling in
hematolymphopoiesis has been studied extensively, little is known of the potential …

Chronic graft-versus-host disease (CGVHD) is one of the most significant complications of
long-term survivors after allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

Chronic graft-versus-host disease (cGVHD) is considered an autoimmune-like disease
mediated by donor CD4+ T cells, but the origin of the autoreactive T cells is still …

Gene expression profiling of human donor T cells before allogeneic hematopoietic cell
transplantation revealed that expression of selected genes correlated with the occurrence of …

Background The major histocompatibility complex (MHC) is the most important genomic
region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic …

Hematopoietic stem cell transplantation (HSCT) today represent standardized biological
manipulation for treating malignant hematological disease, genetic and autoimmune …