[HTML][HTML] Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place …

V Chandrasekar, JL Dreyer - Neuropsychopharmacology, 2011 - nature.com
Molecular adaptations underlying drug seeking and relapse remain largely unknown.
Studies highlight post-transcriptional modifications mediated by microRNAs (miRNAs) in …

The interactive effects of environmental enrichment and extinction interventions in attenuating cue-elicited cocaine-seeking behavior in rats

KJ Thiel, B Engelhardt, LE Hood, NA Peartree… - Pharmacology …, 2011 - Elsevier
Cues associated with cocaine can elicit craving and relapse. Attempts have been made to
employ extinction therapy, which is aimed at attenuating the incentive motivational effects of …

Accumbens shell AMPA receptors mediate expression of extinguished reward seeking through interactions with basolateral amygdala

EZ Millan, GP McNally - Learning & Memory, 2011 - learnmem.cshlp.org
Extinction is the reduction in drug seeking when the contingency between drug seeking
behavior and the delivery of drug reward is broken. Here, we investigated a role for the …

Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration

MB Ghasemzadeh, P Vasudevan, C Giles, A Purgianto… - Brain research, 2011 - Elsevier
Glutamate signaling in prefrontal cortex and ventral tegmental area plays an important role
in the molecular and behavioral plasticity associated with addiction to drugs of abuse. The …

The acute and chronic effects of combined antipsychotic–mood stabilizing treatment on the expression of cortical and striatal postsynaptic density genes

C Tomasetti, C Dell'Aversano, F Iasevoli… - Progress in Neuro …, 2011 - Elsevier
The detection of changes in postsynaptic gene expression after the administration of mood
stabilizers, alone or in combination with antipsychotics, and antidepressants in animal …

The extinction of drug seeking: a role for the nucleus accumbens shell

Z Millan - 2011 - unsworks.unsw.edu.au
Relapse following abstinence from drug use remains the major impediment for the treatment
of addiction. Major advances have been made in understanding the brain systems that …