Reactive oxygen species and thiol antioxidants, including glutathione (GSH), regulate innate
immunity at various levels. This review outlines the redox-sensitive steps of the cellular …

Acute lung injury (ALI) and its more severe form of clinical manifestation, the acute
respiratory distress syndrome is associated with significant dysfunction in air exchange due …

Coptis chinensis has been used in traditional Chinese medicine to treat inflammatory
symptoms. Berberine is the main alkaloid compound of C. chinensis. This study utilized a …

Sepsis is a systemic inflammatory response to infection and a major cause of morbidity and
mortality. Sildenafil (SLD) is a selective and potent inhibitor of cyclic guanosine …

The causative/regulatory connections between changes in tissue redox state and fever
induction were investigated herein. Wherefore, LPS, the primary element of bacterial cell …

The bursa of Fabricius (BF) is a central immune organ in birds, and some peptides from
chicken BF have demonstrated important immune functions. Here, a new 626.27 Da …

Precise control of the LPS stimulation in the lung modulates inflammation and airway
hyperresponsiveness involving the well-known TLR4/NF-κB pathway. As a consequence …

Microglia are the main cellular source of oxidation products and inflammatory molecules in
the brain during aging. The accumulation of mitochondrial DNA (mtDNA) oxidative damage …

Introduction Our purpose was to investigate variation within the IL-32 promoter and gene,
and susceptibility to and outcomes from infection associated acute lung injury (ALI). Methods …

Ferritin is a positive acute phase reactant, exhibiting increased levels in blood during the
acute phase response. Nevertheless, the precise role of ferritin as an acute phase reactant …