Flupirtine antinociception in the rat orofacial formalin test: an analysis of combination therapies with morphine and tramadol
A Capuano, A De Corato, M Treglia, G Tringali… - Pharmacology …, 2011 - Elsevier
Combination therapy with two drugs is a straightforward strategy to improve the risk–benefit
ratio of analgesic treatments. Flupirtine is a non-opioid analgesic drug acting via the …
ratio of analgesic treatments. Flupirtine is a non-opioid analgesic drug acting via the …
In vivo sodium salicylate causes tolerance to acute morphine exposure and alters the ability of high frequency stimulation to induce long-term potentiation in …
Effects of morphine on synaptic transmission and plasticity in the hippocampus area CA1
following in vivo sodium salicylate and the potential molecular mechanism were …
following in vivo sodium salicylate and the potential molecular mechanism were …
[PDF][PDF] Codeine did not increase analgesic efficacy of coxibs in contrast to that of paracetamol or ibuprofen: isobolographic analysis in mice
M Janovsky, M Krsiak - Neuroendocrinology Letters, 2011 - nel.edu
OBJECTIVES: There is good evidence that opioids can potentiate analgesic activity of some
older non-opioid analgesics (such as paracetamol or ibuprofen) but it is not known whether …
older non-opioid analgesics (such as paracetamol or ibuprofen) but it is not known whether …
Preclinical assessment of drug combinations for the treatment of pain: isobolographic and dose-addition analysis of the opioidergic system
BD Fischer - CNS & Neurological Disorders-Drug Targets …, 2011 - ingentaconnect.com
Opioid analgesics are the most frequently prescribed medications for the treatment of
moderate or severe pain; however, their use is constrained by unwanted side effects. One …
moderate or severe pain; however, their use is constrained by unwanted side effects. One …
Investigating the association between P2X7 receptors, microglia and the actions of morphine
SJ Medhurst - 2011 - era.ed.ac.uk
P2X7 receptors belong to a family of membrane bound ion channels which are activated by
extracellular ATP, resulting in the opening of a non-selective cation channel. After prolonged …
extracellular ATP, resulting in the opening of a non-selective cation channel. After prolonged …
Možnosti potenciácie účinku neopioidných analgetík
M Janovský - 2011 - dspace.cuni.cz
Na tomto mieste by som sa rád poďakoval môjmu školiteľovi, prof. MUDr. Miloslavovi
Kršiakovi, DrSc., za inšpiratívne vedenie a cenné rady, ktoré mi behom postgraduálneho …
Kršiakovi, DrSc., za inšpiratívne vedenie a cenné rady, ktoré mi behom postgraduálneho …