Therapeutic targets for the management of peripheral nerve injury-induced neuropathic pain

A Singh Jaggi, N Singh - … Formerly Current Drug Targets-CNS & …, 2011 - ingentaconnect.com
Neuropathic pain is a debilitating form of treatment resistant chronic pain and responds
poorly to the clinically available therapies. Studies from animal models of neuropathic pain …

Tonic inhibition of chronic pain by neuropeptide Y

B Solway, SC Bose, G Corder… - Proceedings of the …, 2011 - National Acad Sciences
Dramatically up-regulated in the dorsal horn of the mammalian spinal cord following
inflammation or nerve injury, neuropeptide Y (NPY) is poised to regulate the transmission of …

Attenuation of pain-related behavior evoked by injury through blockade of neuropeptide Y Y2 receptor

D Sapunar, K Vukojevic, S Kostic, L Puljak - Pain, 2011 - journals.lww.com
Neuropeptide Y (NPY) has an important but still insufficiently defined role in pain
modulation. We therefore examined the ability of NPY to modulate experimentally induced …

[图书][B] The role of Y1R-expressing dorsal horn interneurons in pain

LL Lemons - 2011 - search.proquest.com
The data presented and discussed in this dissertation provides insight into the role of Y1R-
expressing dorsal horn interneurons in pain. Rats injected with 750ng NPY-sap were less …

Neurochemistry of Endogenous Antinociception

G Horvath - Neurochemical Mechanisms in Disease, 2011 - Springer
It is well known that a multitude of ligands and receptors are involved in the nociceptive
system, and some of them increae, whereas others inhibit the pain sensation both …