Progress and challenges in translating the biology of atherosclerosis

P Libby, PM Ridker, GK Hansson - Nature, 2011 - nature.com
Atherosclerosis is a chronic disease of the arterial wall, and a leading cause of death and
loss of productive life years worldwide. Research into the disease has led to many …

Atherosclerosis: current pathogenesis and therapeutic options

C Weber, H Noels - Nature medicine, 2011 - nature.com
Coronary artery disease (CAD) arising from atherosclerosis is a leading cause of death and
morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism …

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and …

Ž Reiner, AL Catapano, G De Backer… - European heart …, 2011 - academic.oup.com
Surveys and registries are needed to verify that real-life daily practice is in keeping with what
is recommended in the guidelines, thus completing the loop between clinical research …

Statins for the primary prevention of cardiovascular disease

F Taylor, K Ward, THM Moore, M Burke… - Cochrane database …, 2011 - cochranelibrary.com
Background Reducing high blood cholesterol, a risk factor for cardiovascular disease (CVD)
events in people with and without a past history of coronary heart disease (CHD) is an …

ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and …

AL Catapano, Ž Reiner, G De Backer… - …, 2011 - atherosclerosis-journal.com
Cardiovascular disease (CVD) due to atherosclerosis of the arterial vessel wall and to
thrombosis is the foremost cause of premature mortality and of disability-adjusted life years …

Inflammatory markers in population studies of aging

T Singh, AB Newman - Ageing research reviews, 2011 - Elsevier
PURPOSE: To review findings from major epidemiologic studies regarding risk factors for
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …

National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 …

F Farzadfar, MM Finucane, G Danaei, PM Pelizzari… - The Lancet, 2011 - thelancet.com
Background Data for trends in serum cholesterol are needed to understand the effects of its
dietary, lifestyle, and pharmacological determinants; set intervention priorities; and evaluate …

Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy

JE McLaren, DR Michael, TG Ashlin, DP Ramji - Progress in lipid research, 2011 - Elsevier
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …

Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists

MH Davidson, CM Ballantyne, TA Jacobson… - Journal of clinical …, 2011 - Elsevier
The National Cholesterol Education Program Adult Treatment Panel guidelines have
established low-density lipoprotein cholesterol (LDL-C) treatment goals, and secondary non …

Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

R Kones - Drug design, development and therapy, 2011 - Taylor & Francis
A recent explosion in the amount of cardiovascular risk and incipient, undetected subclinical
cardiovascular pathology has swept across the globe. Nearly 70% of adult Americans are …